I added this as a comment in the long NIH TIL thread but I also wanted to add it as a post too.
A new biotech was announced today which among their plans are what appears to be commercialization of the NIH TIL trial our own Sleen is doing so well on. They haven't announce yet types of cancer they will try to go after (melanoma is a no-brainer) but getting it to commercial stage is a huge step forward for all cancer types responding. It is not your average biotech - it is fronted by very big business & science people in the field. Commercializing the TIL trial is what will be needed t to get it to the masses. The NIH can provide the proof-of-principle with trial heroes like Sleen but they can't handle & help large numbers of people. The immunotherapy wave continues to build! http://www.fiercebiotech.com/story/thir ... 2015-09-30
-DK
Neon Therapeutics - TIL ImmunoTherapy
Neon Therapeutics - TIL ImmunoTherapy
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/
2016 Colondar 2.0 Model
DK37 Science Posts List
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/
2016 Colondar 2.0 Model
DK37 Science Posts List
Re: Neon Therapeutics - TIL ImmunoTherapy
I hope this thing move fast with more flexible rules so patients like my dad and others can get in.
Father 58 yo , Colon cancer IV + 4 Lymph. 7/2015
K-ras Mutant,GNAS,FBXW7,PIK3CA, MSI-low
4 cycles irinotecan+FU5
developed abdominal met + lung met...Failed
4 cycle Oxaliplatin+folfox. peri met growing...Failed
unofficial trial !!!
K-ras Mutant,GNAS,FBXW7,PIK3CA, MSI-low
4 cycles irinotecan+FU5
developed abdominal met + lung met...Failed
4 cycle Oxaliplatin+folfox. peri met growing...Failed
unofficial trial !!!
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