I want to share my story in hopes that it might help others dealing with the same issue. By day 15 of chemoradiotherapy the ring of fire had me in unimaginable agony (well most of you can probably imagine, but I had no idea what I was in for at the time). I tried everything the doctors were willing to give me, with no luck. Proctofoam, lidocaine, Vicodin. Nothing helped, not even a little bit. I was desperate for relief and quite honestly, I didn't know how I was going to be able to get through the rest of treatment.
Then my surgeon came across a trial that had successfully used Carafate for proctitis. It's an oral drug that is used for stomach ulcers, but she told me to use it as an enema. It was a bit weird because it's hot pink and smells like bubblegum

however, within minutes the pain was cut in half and within an hour it was totally gone. A few hours later I had a BM, 100% pain free. For me, the bubblegum enema is giving me the ability to get to the end of radiation.
I really encourage others that are dealing with the ring of fire to talk to their doctors about Carafate!