Was this study mentioned/posted already?
http://www.healio.com/hematology-oncolo ... ogy%20news
JFrog wrote:We have been doing this stuff for 3 years and the main thing I have learned is that you MUST become your own advocate. We have been to numerous institutions and MDA is our main one and at each, some practitioners don't really think about you except while you are in their office while others do everything they can to help you. One must be as informed as possible and ask questions and be very pushy, even if it is not your nature. I am a healthcare provider myself and this has taught me to be much more of an advocate for each of my patients. By the way my wife is doing a targeted therapy trial at MDA now.
JFrog wrote:She is MSS. Therefore not a good candidate for the PD-1's yet. She is in a study for the p53 mutation which many CRCs have. It is Vorinostat and MLN9708. There has been some good responses in phase I but only a few CRCs were involved, <10. If you haven't tried yet and go to MDA often, get you onc to refer you to the Center for Targeted Therapies there at MDA. They have a lot to offer in way of trials.
JFrog wrote:She is MSS. Therefore not a good candidate for the PD-1's yet. She is in a study for the p53 mutation which many CRCs have. It is Vorinostat and MLN9708. There has been some good responses in phase I but only a few CRCs were involved, <10. If you haven't tried yet and go to MDA often, get you onc to refer you to the Center for Targeted Therapies there at MDA. They have a lot to offer in way of trials.
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