As you don't know yet what is going on with that ovarian mass, assuming it is a CRC met or tumorous, here's our approach:
Sometime pre-surgery, is
the time to get
a full suite of blood markers run. Doctors that won't understand this are replaced as obsolete or defective. If medical serfdom or technology is a regional problem, we do it out of the region/country, as cheaply as possible.
Direct,
functional testing on your live tumor cells is likely the quickest, surest way to find a functioning treatment combination. Xenografts and cultured cells will not be as representative as actual tumor cells. The primary reason I'd do xenograft or cultured cells, is if the viable sample(s) were too small (<1 gram) for direct testing. In any case, our best lab result seemed to agree well with the cumulative blood tests.
You were responsive to 5FU formulas. For things that sprouted up in too many places, daily, metronomic 5FU in multitarget combos work well for us. For quiescent circulating and adherent cell clusters, xeloda may not be the optimal oral maintenance drug, since it first needs to be metabolized by
functioning tumor cells. I think the Japanese had better results with metronomic combos on circulating cells, first with an oral 5FU(!!) backbone and later, tegafur-uracil, a cheap oral 5FU based generic from Asia. UFT is the original brand name based on the original component abbreviations, FT and U.