Postby sjring » Mon Mar 23, 2015 3:19 pm
I know there is some controversy on the benefits of Avastin. I should mention that I do take Avastin as part of my chemo protocol and it is covered by my insurance.
I don't want to quote any specific numbers because I have a lot of numbers jumbled in my head at the moment. But if I recall correctly, that while Avastin has shown an increase in survivability time, it was a relatively short increase relative to the cost. At that point, absent other considerations (like side effects and whether you can afford the out-of-pocket costs), it comes down to whether you think the increased time (again knowing everyone responds differently and statistics tend to break down at the individual patient level) is worth the cost. Personally, if I can afford it and I can have a good QOL I'll take every day I can get.
As far as side effect, while I'm sure there are others, the one I've keyed into is that it can push up blood pressure, and my BP has to be under a certain number in order to receive the dose. I also recall that the started the Avastin infused over a longer time and then as I tolerated it, shortened the infusion time. Other than that I think most of my side effects come from the 5-FU. The Oxili was the worst of what I had.
Best of luck to your Dad!
50 YO Husband & father of 2 teenagers.
DX 9/9/13 Stage 4 cc (at age 48)
16 Rounds FOLFOX + Avastin (Oct-13 to May-14)
Maintenance chemo - Avastin & 5-FU infusions (Jun-14 to Jul-15)
Jul-15: Mets to lymph nodes, resuming FOLFOX
Sep-15: MRI showed stability, back to maintenance chemo.