Oxaliplatin is the drug used most often with 5-FU and Leucovorin or Xeloda as first line treatment for CRC. A large number of people here are either on it or have had it. As for its effectiveness for some rather good. It all depends on the details of your dad's diagnosis. Your signature doesn't say much about it except for it being Dukes C? This isn't the normal staging most of us are use to seeing and off hand I am not sure what to compare that to. You also need to define what you mean by success. Will it cure him? Depends..
But if the oncologist recommends he be on it. In all likelihood he should be. There are not many first line treatments to chose from. Later its possible they could perhaps add Avastin to the mix.
There are serious side effects associated with Oxaliplatin. The links provided by ritz75 should be a good start towards letting you know what to expect. Your dad's oncologist should have gone over this with him.
DW 53 dx Jun 2013
CT mets Liver Spleen lung. IVb CEA~110
Jul 2013 Sig Resct
8/13 FolFox,Avastin 12Tx mild sfx, Ongoing 5-FU Avastin every 3 wks.
CEA: good marker
7/7/14 CT Can't see the spleen Mets.
8/16/15 CEA Up, CT new abdominal mets. Iri, 5-FU, Avastin every 2 wks.
1/16 Iri, Erbitux and likely Avastin (Trial) CEA going >.
1/17 CEA up again dropped from Trial, Mets growth 4-6 mm in abdomen
5/2/17 Failed second trial, Hospitalized 15 days 5/11. Home Hospice 5/26, at peace 6/4/2017