Higher Vitamin D levels and colorectal cancer survival

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vilca11
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Location: Moscow, Russia; Baltimore, USA 1992; Vilcabamba, Ecuador 2012

Re: Higher Vitamin D levels and colorectal cancer survival

Postby vilca11 » Wed Jul 08, 2015 9:56 am

Vit D levels are very hard to rise with sun only. You need to be at certain time of the day (around 12pm) to be full body naked for 20-30min to get a special ray diapason that is beneficial for Vit D increase. Every day and for a long time. That is why even living in Cali or Florida does not make much difference. When studies were done, the further from Equator people are, the more cancer they have, provided all other food/environmental conditions are the same.

For the cancer patients the levels, to the best of my knowledge, must be from 80 to 100 ng/ml. I did not read the bibliography that Maia included, just my personal experience/reading. I know that when I stop taking Vit D, I have a drop down to 40, but normally it is in 80's with a maintenance dose. And I do live on Equator.
Vilca
11/2005 CC stage 1, F,50yo@dx
Mod dif adenocar, MSS, APC, TP53, CEAs1.6-4.8
1/12 1met liver@Vena Cava, RFA, 3oxi,11 5FU
8/13 2 mets same place,SBRT
4/14 2 Xeliri+Avastin
5/14 Nano Knife liver same 2 mets
6/14 2 Xeliri, ADAPT
4/15 PET, 2 same mets,Cryo Liver
5/15 MJ Oil, Herbs, Suppl, ADAPT
10/15 PET, same area, doubled in size, high SUV
10/15 RH, HAI, visceral involv., no LN
2/16 red FF, 50% red dose FUDR, CEA trends up
3/16 CT, PET, MRI L.Lobe all in small tumors
4/16 No acceptable options, going home

JDinNC
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Location: Murphy, N.C.

Re: Higher Vitamin D levels and colorectal cancer survival

Postby JDinNC » Wed Jul 08, 2015 2:45 pm

Just because you live in a sunny state doesn't mean you are getting enough Vit D. I lived 50 years in South Florida from childhood to adulthood. Though I spent my teens in the sun, my adult years was mostly just working outdoors. At the time of my cancer diagnose, my Vit.D level was low so my doctor put me on pills. My readings are in the low 90's now and my doctor wants me to cutback from 1,000 to 500. I just don't feel comfortable doing that yet.
61 y/o female @ DX...........
T3N0M1
6/13 DX- stage 4
Sigmoid colon cancer.
One met to lung
7/13 colon resection
8/13 lung resection
FOLFOX with avastin
7/17 four years....NED

MELANOMA
63 y/o @ DX
6/15 stage 2a
7/15 surgery on arm
7/15 NED
4/16 recurrance
5/16 remove metastasis from back
5/16. Started immunotherapy
8/16 discontinue treatment

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dianetavegia
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Re: Higher Vitamin D levels and colorectal cancer survival

Postby dianetavegia » Mon Nov 06, 2017 4:23 pm

UPDATE: Labcorp now has 39 as 'low' and 100 as 'high norm'. I keep my D3 as close to 100 as possible but it takes 6,000 iu's daily and I live in Georgia.

As we age, our skin doesn't convert sunlight like it used to so more Vit. D3 is needed.
Stage IIIB cc surgery 1/7/09. 5/17 nodes. 12 tx FOLFOX
Stage IVa 2/15/12. CEA 6.4 PET = 1.5cm liver met. HR 4/11/12 No chemo

Nine years 3 months since my original dx and Six years post liver resection.
NED April 2018!
“O Lord my God, I cried out to You, And You healed me.”
Psalms 30:2

NHMike
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Re: Higher Vitamin D levels and colorectal cancer survival

Postby NHMike » Mon Nov 06, 2017 6:02 pm

My sister had genetic testing done and found that she has a recessive trait where Vitamin D3 is poorly absorbed by the body and it looks like I have it as well.
6/17: ER rectal bleeding; Colonoscopy
7/17: Stage 3B rectal. T3N1bM0. 5.2 x 4.5 x 4.3 cm. Lymphs: 6 x 4 mm, 8 x 6, 5 x 5
7/17-9/17: Xeloda +radiation
7/5: CEA 2.7; 8/16: 1.9; 9/8: 1.8; 11/30: 0.6; 12/20 1.4; 1/10 1.8; 1/31 2.2; 2/28 2.6; 4/10 2.8
MSS, KRAS G12D
10/17: 2.7 x 2.2 x 1.6 cm (-90%). Lymphs: 3 x 3 mm (-62.5%), 4 x 3 (-75%), 5 x 3 (-40%). 5.1 CM from AV
10/17: LAR, Temp Ileostomy, Path Complete Response
CapeOx 8 cycles 12/17-6/18

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LPL
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Location: Europe

Re: Higher Vitamin D levels and colorectal cancer survival

Postby LPL » Mon Nov 06, 2017 7:02 pm

I wonder what is the hen and the egg here..?
Hubby always had higher vitamin D3 test result than me before he was diagnosed with CRC. As soon as he got diagnosed I took a test on us both and suddenly he had quite a bit lower than me. (He had 29ng/ml and I had 45). Now after surgery and treatment he is back to a good vitamin D3 level again and he has not been supplementing a high amount. To me it feels like the Colon cancer caused his vitamin D3 to go down.
DH @ 65 DX 4/11/16 CC recto-sigmoid junction
Adenocarcenoma pt 35x15x9mm G3(biopsi) G1(surgical)
Mets 3 Liver resectable
T4aN1bM1a Stage IVa 2/9 LN
MSS, KRAS-mut G13D
CEA & CA19-9: 5/18 2.5 78 8/17 1.4 48 2/14/17 1.8 29
4 Folfox 6/15-7/30 (b4 liver surgery) 8 after
CT: 8/8 no change 3/27/17 NED for now :D
:!: Steroid induced hyperglycemia dx after 3chemo .. hospitalized, insulin -> Metformin
Surgeries (open):
3/18 Emergency colostomy 5/23 Primary+gallbl+colostomy reversal (+port) 9/01 Liver mets

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Atoq
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Re: Higher Vitamin D levels and colorectal cancer survival

Postby Atoq » Tue Nov 07, 2017 9:35 am

I don’t know, I live in Norway and my D3 vit at diagnosis was 94, so quite high. Actually all the parameters checked from blood, including the markers for CRC where in the normal range :|

Best

Claudia
45 year old, mother of 2
Dx rectal cancer October 2017
At least T3N2aMX (suspect metastasis to one lung 8 mm)
Lynch negative
Neoadjuvant chemoradiotherapy Xeloda + 25x2 Gy
05.12.17 laparotomic surgery for blockage, colostomy
25.01.18 laparotomic lar, hysterectomy, ileostomy
05.03.18 core needle biopsy of lung, updated to stage IV
07.05.18 CAT scan, lung metastasis 11 mm
04.06.18 ileostomy reversal
26.06.18 wedge VATS surgery

rp1954
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Joined: Mon Jun 13, 2011 1:13 am

Re: Higher Vitamin D levels and colorectal cancer survival

Postby rp1954 » Tue Nov 07, 2017 5:54 pm

Just be aware about which units your country's labs use for 25 hydroxy vitamin D in blood. It's a huge difference.
For example:
37.7 ng/ml = 94 nmol/l
vs
94 ng/ml = 235 nmol/l
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC

canadiandaughter
Posts: 674
Joined: Sun Aug 17, 2014 11:19 am

Re: Higher Vitamin D levels and colorectal cancer survival

Postby canadiandaughter » Tue Nov 07, 2017 7:00 pm

There is a book written about taking vitamin D to help against cancer. I cant recall the name right now, but my dads GP recommended that we look into it when my dad was taking treatments, he said if it was him he would be on it. It was excessive amounts, but you needed to take vitamin K to help with it, which my dad could not take while on blood thinners. I have no idea if it is legit, but might be something to check out. If it can't hurt you what is the harm in it!
DD to 81 year old father
dx 24/07/14 iv cc mets liver/lung
folifiri started 19/07/14
shrinkage of all mets
growth in the liver,started folfox/avastin 80% 13/01/16
reduced to 70% due to side effects 27/01/16
First scan on folfox shows shrinkage in lungs, but liver just stable
6 rounds of vectibix-fail. 3cm growth and new spots showing Waiting for panel recommendations
At peace January 8, 2017

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Atoq
Posts: 264
Joined: Wed Oct 25, 2017 9:31 am

Re: Higher Vitamin D levels and colorectal cancer survival

Postby Atoq » Tue Nov 07, 2017 7:48 pm

rp1954 wrote:Just be aware about which units your country's labs use for 25 hydroxy vitamin D in blood. It's a huge difference.
For example:
37.7 ng/ml = 94 nmol/l
vs
94 ng/ml = 235 nmol/l


The normal range is 50-150, my analysis report does not specify the unit, but I guess 94 is in the middle of the range, so rather good.

Beat

Claudia
45 year old, mother of 2
Dx rectal cancer October 2017
At least T3N2aMX (suspect metastasis to one lung 8 mm)
Lynch negative
Neoadjuvant chemoradiotherapy Xeloda + 25x2 Gy
05.12.17 laparotomic surgery for blockage, colostomy
25.01.18 laparotomic lar, hysterectomy, ileostomy
05.03.18 core needle biopsy of lung, updated to stage IV
07.05.18 CAT scan, lung metastasis 11 mm
04.06.18 ileostomy reversal
26.06.18 wedge VATS surgery

rp1954
Posts: 1325
Joined: Mon Jun 13, 2011 1:13 am

Re: Higher Vitamin D levels and colorectal cancer survival

Postby rp1954 » Tue Nov 07, 2017 8:50 pm

Looks like your level is reported in nmol/l as the unit of measure. That serum vitamin D range would be 20 - 60 ng/ml, which is typical. Some researchers and doctors think that there are therapeutic regimes at higher levels, with a slightly prescriptive application (e.g. extra menatetrenone, no excess calcium).
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC


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