TIL Immunotherapy at NCI

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teri3
Posts: 386
Joined: Fri Jan 09, 2015 11:03 am

Re: TIL Immunotherapy at NCI

Postby teri3 » Wed May 02, 2018 7:13 am

Going this Sunday May 6th to be admitted for my TIL harvest surgery, apheresis is scheduled for Friday 11. Then the wait begins! I'll update as I know more.
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(

User avatar
Sleen
Posts: 313
Joined: Tue Jan 14, 2014 7:41 am
Location: Detroit
Contact:

Re: TIL Immunotherapy at NCI

Postby Sleen » Wed May 02, 2018 8:32 am

Good luck!

Celine
my blog: Cancer Riot

NED since April 2016!
April 2016: lower left lung lobectomy. NED
8 mo. f/u: 1 of 7 tumors progressed.
6 mo. f/u PR confirmed (Jan 2016)
Jul 2015: NIH TIL trial NCT01174121 NCI/NIH Surgery Branch FAQ
Dec 2015 stage IV w/bilateral lung mets
FOLFOX + Radiation (bladder)
KRAS G12D :: MSS
dx Sep 2013 @47yo: IIIc T4b N2b MX [bladder invasion, 17/21 lymph nodes]

Married 28 yrs. kids: 22, 19, 15, 11, 9
SE Michigan home schooler, unemployed mechanical engineer, and programmer.

DAS43
Posts: 51
Joined: Thu Aug 18, 2016 8:10 pm

Re: TIL Immunotherapy at NCI

Postby DAS43 » Wed May 02, 2018 9:15 am

teri3 wrote:Going this Sunday May 6th to be admitted for my TIL harvest surgery, apheresis is scheduled for Friday 11. Then the wait begins! I'll update as I know more.
Teri


Sending prayers for a quick recovery and a successful outcome.
11/13 total blockage DX colon cancer IV, colostomy
1/14 folfox
3/14 liver resection NED
8/14 last chemo
12/14 colostomy reversal
8/16 3mets to lungs
10/16 trial at NIH TIL
9/17 partial responder to TIL protocol

Lee
Posts: 5678
Joined: Sun Apr 16, 2006 4:09 pm

Re: TIL Immunotherapy at NCI

Postby Lee » Wed May 02, 2018 4:05 pm

teri3 wrote:Going this Sunday May 6th to be admitted for my TIL harvest surgery, apheresis is scheduled for Friday 11. Then the wait begins! I'll update as I know more.
Teri


Ditto on good luck.

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 10 years and counting!

teri3
Posts: 386
Joined: Fri Jan 09, 2015 11:03 am

Re: TIL Immunotherapy at NCI

Postby teri3 » Wed May 02, 2018 9:08 pm

Thanks guys. I'm pretty excited to become part of something like this.
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(

DAS43
Posts: 51
Joined: Thu Aug 18, 2016 8:10 pm

Re: TIL Immunotherapy at NCI

Postby DAS43 » Thu Jun 14, 2018 3:15 pm

3 month check up today at NIH. Yesterday I had ct scan and brain MRI. My scans have not changed, which is great news! I will be going back at the end of September.
11/13 total blockage DX colon cancer IV, colostomy
1/14 folfox
3/14 liver resection NED
8/14 last chemo
12/14 colostomy reversal
8/16 3mets to lungs
10/16 trial at NIH TIL
9/17 partial responder to TIL protocol

User avatar
Sleen
Posts: 313
Joined: Tue Jan 14, 2014 7:41 am
Location: Detroit
Contact:

Re: TIL Immunotherapy at NCI

Postby Sleen » Thu Jun 14, 2018 3:29 pm

AMAZING!
So happy for you :) :) :)

Celine
my blog: Cancer Riot

NED since April 2016!
April 2016: lower left lung lobectomy. NED
8 mo. f/u: 1 of 7 tumors progressed.
6 mo. f/u PR confirmed (Jan 2016)
Jul 2015: NIH TIL trial NCT01174121 NCI/NIH Surgery Branch FAQ
Dec 2015 stage IV w/bilateral lung mets
FOLFOX + Radiation (bladder)
KRAS G12D :: MSS
dx Sep 2013 @47yo: IIIc T4b N2b MX [bladder invasion, 17/21 lymph nodes]

Married 28 yrs. kids: 22, 19, 15, 11, 9
SE Michigan home schooler, unemployed mechanical engineer, and programmer.

teri3
Posts: 386
Joined: Fri Jan 09, 2015 11:03 am

Re: TIL Immunotherapy at NCI

Postby teri3 » Tue Aug 07, 2018 7:00 pm

Got my good news today my cells are growing! Going back to NIH to review recent scans... which are good stable or shrinking lung mets after 5 treatments folfiri+ avistan...Thursday August 16th. The are starting testing on my T cells. Possible start in the trial the end of September.... fingers crossed
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(

Lee
Posts: 5678
Joined: Sun Apr 16, 2006 4:09 pm

Re: TIL Immunotherapy at NCI

Postby Lee » Wed Aug 08, 2018 1:17 pm

teri3 wrote:Got my good news today my cells are growing! Going back to NIH to review recent scans... which are good stable or shrinking lung mets after 5 treatments folfiri+ avistan...Thursday August 16th. The are starting testing on my T cells. Possible start in the trial the end of September.... fingers crossed
Teri


CONGRATULATIONS!!!

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 10 years and counting!

User avatar
LPL
Posts: 410
Joined: Fri Apr 22, 2016 12:49 am
Location: Europe

Re: TIL Immunotherapy at NCI

Postby LPL » Thu Aug 09, 2018 2:54 pm

teri3 wrote:Got my good news today my cells are growing! Going back to NIH to review recent scans... which are good stable or shrinking lung mets after 5 treatments folfiri+ avistan...Thursday August 16th. The are starting testing on my T cells. Possible start in the trial the end of September.... fingers crossed
Teri

Sounds wonderful :)
Keeing my fingers crossed this will work for you!
DH @ 65 DX 4/11/16 CC recto-sigmoid junction
Adenocarcenoma pt 35x15x9mm G3(biopsi) G1(surgical)
Mets 3 Liver resectable
T4aN1bM1a Stage IVa 2/9 LN
MSS, KRAS-mut G13D
CEA & CA19-9: 5/18 2.5 78 8/17 1.4 48 2/14/17 1.8 29
4 Folfox 6/15-7/30 (b4 liver surgery) 8 after
CT: 8/8 no change 3/27/17 NED for now :D
:!: Steroid induced hyperglycemia dx after 3chemo .. hospitalized, insulin -> Metformin
Surgeries (open):
3/18 Emergency colostomy 5/23 Primary+gallbl+colostomy reversal (+port) 9/01 Liver mets

teri3
Posts: 386
Joined: Fri Jan 09, 2015 11:03 am

Re: TIL Immunotherapy at NCI

Postby teri3 » Thu Aug 09, 2018 3:54 pm

thanks fingers crossed
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(

User avatar
Sleen
Posts: 313
Joined: Tue Jan 14, 2014 7:41 am
Location: Detroit
Contact:

Re: TIL Immunotherapy at NCI

Postby Sleen » Sun Sep 16, 2018 8:24 am

Checking in to report that follow-up FOURTEEN was all good. I am still NED. :) :) :)
Next follow-up in six months.

Celine
my blog: Cancer Riot

NED since April 2016!
April 2016: lower left lung lobectomy. NED
8 mo. f/u: 1 of 7 tumors progressed.
6 mo. f/u PR confirmed (Jan 2016)
Jul 2015: NIH TIL trial NCT01174121 NCI/NIH Surgery Branch FAQ
Dec 2015 stage IV w/bilateral lung mets
FOLFOX + Radiation (bladder)
KRAS G12D :: MSS
dx Sep 2013 @47yo: IIIc T4b N2b MX [bladder invasion, 17/21 lymph nodes]

Married 28 yrs. kids: 22, 19, 15, 11, 9
SE Michigan home schooler, unemployed mechanical engineer, and programmer.

stu
Posts: 848
Joined: Sat Aug 17, 2013 5:46 pm

Re: TIL Immunotherapy at NCI

Postby stu » Sun Sep 16, 2018 8:40 am

Whoop . Fantastic news . Keep it coming .
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared

sdino
Posts: 63
Joined: Tue Mar 28, 2017 5:32 pm

Re: TIL Immunotherapy at NCI

Postby sdino » Tue Sep 25, 2018 7:46 am

Sleen wrote:Checking in to report that follow-up FOURTEEN was all good. I am still NED. :) :) :)
Next follow-up in six months.

Celine


Great News !
Caregiver for Wife 53 yrs old
DX:11/16-CC sigmoid colon
Lung Mets: Bilateral ranging 4mm-1.5cm
MSS, KRAS-mut G12D; TP53
Folfox/Avastin + Oxi 11/16 to 5/17, Xeloda+Avastin 8/17
CT Scans: 5/17 colon & lung met shrinkage,11/17 and 1/18 slight progression; 5/18, 7/18 stable lungs/colon
NCI YOUNGER TIL Trial NCT03412877 awaiting progression - 1/18 VATs lung 2 mets wedge resect
CEA: 16 - 11/16; 0.6 - 5/17; 3.0 - 11/17; 4.4 - 1/18; 5.7 - 2/18; 4.9 - 3/18, 4.0 - 5/18, 7/18 - 6.8, 9/18 - 5.1

Eleda
Posts: 167
Joined: Thu Dec 28, 2017 2:28 am
Facebook Username: adele Morgan
Location: Ireland

Re: TIL Immunotherapy at NCI

Postby Eleda » Tue Sep 25, 2018 2:29 pm

So good to hear some great news,
Long may it last
Adele X
SWF, 47
Mom to 3 sons 6/8/12
Dec4th 2017 colonoscopy for minor intermittent rectal bleeding during Summer
CEA 4.4
DX T3 L3C M0 2.5/3 cm above AV.
JAN 3RD started 1650mg Zelda 2xday, with 28 radiation
Did tagamet 800mg daily and 75mg IV VIT C WEEKLY UNTIL SURGERY and
Tumor reduce by 80% 1 LN still remaining
TATME May10th, temp illeostomy
10/07/2018 CEA 3
MMR INTACT
Began FOLFOX July 10th
24/08/2018 Allergic reaction so next infusion lucovorin and 5fu
CEA 4
Second attempt with oxi aug 12th


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