Postby stars9979 » Thu Sep 04, 2014 11:35 pm
FOUND IT:
Report this postReply with quoteRe: what is the max tumor size to be deemed surgical?
by SkiFletch » Thu Jul 31, 2014 8:46 am
The size of the tumor on a scan is not the determining factor for surgical candidacy. The largest factor for determining resectability is the distance from the edge of the tumor (in the scan) to an organ/vessel/structure that is NOT removable. I'll take some time to explain why, cause if you understand it, you might accept the decision easier.
The visible size of the tumor on CT is smaller than the actual coverage of invasive cancer cells. A met does not grow like a perfect sphere with clean lines of demarcation. If you cut one out and look at it under a microscope, one can see the "edges" of the tumor infiltrate a long way into "healthy" tissue. It's a swirling, tendrily pattern that happens at a cellular level, something even the best CT scanners in the world can't see. The length of this cellular-level infiltration can be anywhere from 1cm, to as much as 4cm from the edge. Generally, a surgeon attempts to get at LEAST 5cm away from the "visible edge" of the tumor to prevent microscopic cells from surviving the surgery, and re-forming a met. This is why you hear they want to get "good margins" when doing surgery. If microscopic cancer cells remain in the margin, the met WILL come back, just a matter of time.
So you mention your mother's liver tumor is in section 7 of the liver. That is all the way to the right, rear, and top of the organ. If her tumor is near the surface of the liver, it's do-able for the surgeon. It's always trickier with the rear segments, but essentially the surgeon chops a wedge out, done. If it's deep within section 7, further to the front and left and say within 3cm of the hepatic artery... Then it's not so simple as the surgeon has to assume that the hepatic artery segment is infiltrated with cancer cells and needs to be removed. They then have to consider removing section 8 as well, and perhaps even the whole right lobe if it's very much too low and close to the main hepatic artery, not just the upper branch of it. That's not an easy open-shut decision as regeneration of an entire lobe is never a sure thing, and the right lobe is the largest portion of the liver.
So, bottom line, there is no specific size of tumor that is operable or not. It's all about the distance from other required vessels/structures/organs.11/13/09 5cm Stage IV 9/25 lymph nodes w/2cm peritoneal met at 29 YoA
12/15/09 LA right hemi-colectomy
6/16/10 Folfox FINISHED
8/10/10 Prophylactic HIPEC
10/9/10 got Married
"Can any one of you by worrying add a single hour to your life."SkiFletch
Posts: 6310
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Caregiver to 54 y/o mom
Dx April 4 2014
Stage IV CC w mets to liver
Illeostomy (temp) 05/05/2014
6 rounds FOLFOX 05/14-08/14
Primary tumor/colon resection/I'll take down 10/27/14