My5-FU, DPD
My5-FU, DPD
Anyone out there whose oncologist uses the My5-FU Test and/or test patients for DPD deficiency?
Mother DX @59 8/14
cln+lvr res 9/14, stage 4
FOLOX+Avs 12-rd 10/14 to 4/15
Reoccurrence, KRAS mutant 11/15
Folfiri 18-rds 11/15-8/16
FOLFIRI with Ramicirumab 28-rds 8/17-9/18
Regorafenib 10/18-10/19
Lonsurf 10/19 onward
Folfox rechallenge 05/20
Regonivo (Opdivo+Stivarga) 08/20
External Peace 09/12/2022
cln+lvr res 9/14, stage 4
FOLOX+Avs 12-rd 10/14 to 4/15
Reoccurrence, KRAS mutant 11/15
Folfiri 18-rds 11/15-8/16
FOLFIRI with Ramicirumab 28-rds 8/17-9/18
Regorafenib 10/18-10/19
Lonsurf 10/19 onward
Folfox rechallenge 05/20
Regonivo (Opdivo+Stivarga) 08/20
External Peace 09/12/2022
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Bev G
- Posts: 5856
- Joined: Thu Jan 07, 2010 11:19 pm
- Facebook Username: Bev Golde
- Location: Quechee, VT
Re: My5-FU, DPD
Hi. DPD is pretty rare:
"Complete DPD deficiency is estimated to occur in about 0.1% of patients, whereas relative DPD deficiency is projected to have an incidence of 3% to 5%"
I don't think most oncologists test for it unless a patient first has or seems to have a pretty awful reaction to 5FU. My onc wound up testing me, because I was just so utterly and completely sick from chemo (the worst she's seen, according to her). I did not have a DPD deficiency.
Bev
"Complete DPD deficiency is estimated to occur in about 0.1% of patients, whereas relative DPD deficiency is projected to have an incidence of 3% to 5%"
I don't think most oncologists test for it unless a patient first has or seems to have a pretty awful reaction to 5FU. My onc wound up testing me, because I was just so utterly and completely sick from chemo (the worst she's seen, according to her). I did not have a DPD deficiency.
Bev
58 yo Type1 DM 48 years
12/09 Stage IV 2/22 nodes + liver met, colon resec
3 tx FOLFIRI, liver resec 4/10
9/10 6 mos off chemo, Neg PET&CTC CEA nl
2/11 finished total 10 rounds chemo
9/13 ^17th clean PET/CT NED for now
12/09 Stage IV 2/22 nodes + liver met, colon resec
3 tx FOLFIRI, liver resec 4/10
9/10 6 mos off chemo, Neg PET&CTC CEA nl
2/11 finished total 10 rounds chemo
9/13 ^17th clean PET/CT NED for now
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