VPS and PSK are different extracts of the mushroom used, Coriolos Versicolor. PSK is the extract which has shown the best results, particularly in Japan. This is the study which refers to the VPS extract causing an increase in the size of the tumors. At the end it is mentioned how PSK had the opposite effect on rats, it's an interesting read.
http://iv.iiarjournals.org/content/19/5/867.longI take 3600 mg because that is also a recommended dose on the package:
"Suggested Use: Adults, take 1-3 capsules, twice daily, on an empty stomach."
I figure the max is fine, as there is no evidence of any type of side effect. The more the merrier.
Al