DCVax-Direct: First Case Study Announced

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janderson
Posts: 679
Joined: Tue Mar 27, 2012 11:46 am

Re: DCVax-Direct: First Case Study Announced

Postby janderson » Fri Jun 27, 2014 12:37 pm

Thanks for the update. This treatment seems to get more encouraging all of the time.
DX 10-05 stage IV
liver resection 12-05 Folfox1-05 to 7-06
Liver resection 8-07 Folfiri 9-07 to 3-08
Liver resection 12-11
Recurrence 2/7/2014, liver, chestwall mets, 16 rounds chemo
7/3/14, y90 radioembolization, steady shrinkage
12/8/14, cryoablation to liver and chest wall
6/1 to 6/26 SBRT radio surgery
7/2 more cryo ablation to right lung
7/16 lung infection drain tube installed
9/4 chest wall resection to remove 2 ribs

janderson
Posts: 679
Joined: Tue Mar 27, 2012 11:46 am

Re: DCVax-Direct: First Case Study Announced

Postby janderson » Mon Jun 30, 2014 12:46 pm

Bumping up. I think this is a great subject that shows a lot of promise.
DX 10-05 stage IV
liver resection 12-05 Folfox1-05 to 7-06
Liver resection 8-07 Folfiri 9-07 to 3-08
Liver resection 12-11
Recurrence 2/7/2014, liver, chestwall mets, 16 rounds chemo
7/3/14, y90 radioembolization, steady shrinkage
12/8/14, cryoablation to liver and chest wall
6/1 to 6/26 SBRT radio surgery
7/2 more cryo ablation to right lung
7/16 lung infection drain tube installed
9/4 chest wall resection to remove 2 ribs

User avatar
Maia
Posts: 2443
Joined: Fri Aug 24, 2012 8:00 am

Re: DCVax-Direct: First Case Study Announced

Postby Maia » Tue Sep 09, 2014 9:02 am

DCVax Direct used in a patient with stage 4 pancreatic cancer whose chemotherapy was stopped

https://www.facebook.com/video.php?v=10100434831905439 (Video)


The National Geographic channel ran a show called Stand Up to Cancer that aired on Friday, September 4. On that show there was a two minute segment on a patient who was diagnosed with stage 4 pancreatic cancer. The patient, Allan Butler, is an employee of Nat Geo and this is how the story found its way into the segment. Northwest Biotherapeutics (NWBO) was not involved in any way in the selection of Mr. Butler’s experience to be included in this program.

An important point of this segment is that it prominently shows and names the physician treating the patient, Dr. Ravi Murthy, and also shows and names the lead investigator for the phase 1 study of DCVax Direct, Dr. Vivek Subbiah. Both are physicians with M.D. Anderson.

"DCVax Direct was used in a patient with stage 4 pancreatic cancer whose chemotherapy was stopped.
The patient, a Nat Geo employee, is stable at 18 months post diagnosis and gives his very positive view of the efficacy of DCVax Direct.
Clinical studies show that 50% of such stage 4 pancreatic patients die within six months and 77% within one year. Perhaps as few as 2-3% survive 18 months.
M.D. Anderson doctors appeared in this segment. This prestigious institution is running the trial and is clearly supportive of DCVax Direct and NWBO.
This is just one patient, but it must be viewed alongside the recent impressive signal of efficacy seen in a sarcoma, another highly aggressive tumor.
The DCVax Direct trial is in its early days for reporting data and these two cases may yet prove to be outliers, but they are very encouraging. "
here

janderson
Posts: 679
Joined: Tue Mar 27, 2012 11:46 am

Re: DCVax-Direct: First Case Study Announced

Postby janderson » Fri Sep 12, 2014 7:08 am

i watched stand up 4 cancer but somehow missed that segment. I am posting because I was just in contact with MD Anderson about this trial yesterday and they want to see. Phase I is closed but phase II is supposed to start at the end of the month. The problem is MD Anderson doesn't know if they will be accepting colon cancer patients for phase II even thought they did for phase I. They said we can look at other trials too. At least I got my foot in the door.

The big dilemma is my blood counts have been crashing and I was refused treatment last week. i am trying again today but I dont know if I should go through with it even if the counts come up enough because I am pretty sure that is one thing they will check for most trials.
DX 10-05 stage IV
liver resection 12-05 Folfox1-05 to 7-06
Liver resection 8-07 Folfiri 9-07 to 3-08
Liver resection 12-11
Recurrence 2/7/2014, liver, chestwall mets, 16 rounds chemo
7/3/14, y90 radioembolization, steady shrinkage
12/8/14, cryoablation to liver and chest wall
6/1 to 6/26 SBRT radio surgery
7/2 more cryo ablation to right lung
7/16 lung infection drain tube installed
9/4 chest wall resection to remove 2 ribs


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