Amitriptyline

Please feel free to read, share your thoughts, your stories and connect with others!
sharpey92
Posts: 53
Joined: Tue Jan 21, 2014 10:22 am

Amitriptyline

Postby sharpey92 » Wed Apr 02, 2014 3:17 am

While I am being re-refered my doctor has put me on something called Amitriptyline which was first made as an anti-depressant, but they now use it for pain.

Never heard of it myself but my mother has had it before and they gave it to her to use as a sedative.

So far as to say so far doesnt seem to be doing anything so far with pain still coming random as ever but willing to give it a chance just to help stop the pain coming.

Has anyone else ever heard of an anti-depressant being used as a pain reliever?

tammylayne
Posts: 2177
Joined: Fri Jul 16, 2010 9:24 am

Re: Amitriptyline

Postby tammylayne » Wed Apr 02, 2014 7:16 am

My husband has severe nerve pain in his groin and down his legs, and amitriptyline has saved him from intolerable pain. It works in about 50% of cases, and if it does...it is important to STAY on it...if you go off and restart it, it might not be as successful. It is also accumulative,,,so give it some time. If it makes you sleepy, you might have to play with when you take it...I know my husband did.

Good luck!!!!
51 F
'06 Stage 1 CC,
'10 Stage 3 Rectal

"You never know how strong you are until you have to become your own hero."

sharpey92
Posts: 53
Joined: Tue Jan 21, 2014 10:22 am

Re: Amitriptyline

Postby sharpey92 » Wed Apr 02, 2014 9:08 am

Thank you for your reply!!

My doc is giving it 2weeks till i next see her to see if they have any effect.

I will keep popping them back, hope they do work, had a bad bout of pain this afternoon.

tif2112
Posts: 114
Joined: Wed Jul 04, 2012 4:23 pm
Facebook Username: tif2112
Location: Henderson, NV

Re: Amitriptyline

Postby tif2112 » Wed Apr 02, 2014 11:01 am

I have taken this for several years for muscle tension headaches. Works very well and keeps my headaches under control.
51 year old female
Henderson, Nv

T3N0M0
2012 DX - Rectosigmoid Mass, Colon Resection, rx - radiation and chemo
07-24-2014 NED
2014 englarge lymph nodes, biopsy of 1 negative
07-07-2015 even bigger enlarged lymph nodes, shown on MRI & CT
2015 biopsy of bone marrow, lymph nodes-negative
3-6-2018 still enlarged lymph nodes, no diagnosis

nicola smith
Posts: 1040
Joined: Thu Oct 07, 2010 9:06 am

Re: Amitriptyline

Postby nicola smith » Wed Apr 02, 2014 1:36 pm

First, my oncologist prescribed gabapentin for my ongoing neuropathy especially from the knees to toe-tips. It did nothing but cause weight gain :cry:. Then I found a cancer pain clinic that prescribed nortriptyline @50mg a day as the next option. They said if that didn't work, there was a whole range of other options to try including methodone.

Although it took a couple of weeks to kick in, the nortriptyline has worked very well :D . I still know I have neuropathy but I am not experiencing it as burning or tingling, just a bit of crunchiness that is easy to ignore. Early side effects of the drug were a slight muzziness in thinking and dry mouth. These sensations went away after a few weeks.

I was VERY surprised to learn that the drug was initially developed as an anti-psychotic :shock: .
UC history
11/09: Dx, CEA 2.9
02/10: colectomy, temp ileo; pT3N1Mx
10/10: 12 Folfox6
03/11: jpouch
2010/11/12/13/14: 6 PET and/or CT's - NED
quarterly 03/2010- 03/2015: CEA range 0.8-1.3
03/2015: discharged to GP :D

User avatar
CRguy
Posts: 10476
Joined: Sun Feb 10, 2008 6:00 pm

Re: Amitriptyline

Postby CRguy » Wed Apr 02, 2014 5:49 pm

nicola smith wrote:I was VERY surprised to learn that the drug was initially developed as an anti-psychotic :shock: .

and another fun fact ... amitriptyline was also used as a mellowing out prozac for kitties for cats with behavioural problems.

Just a note : all these drugs basically should not be stopped cold turkey ... they are usually weaned On and OFF to avoid some potentially nasty side effects... but check with your docs about specifics.

Cheers All
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
17 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

Cathie
Posts: 78
Joined: Fri Mar 28, 2014 12:09 pm

Re: Amitriptyline

Postby Cathie » Wed Apr 02, 2014 7:35 pm

I have a home for the mentally ill and some of them take amitriptyline. I also take it for restless leg syndrome.

Cathie
Dx'd colo rectal cancer Oct 2002
radiation chemo November December 2002
Surgery Mar 2003 which was a temp ileo
Summer of 2003 more chemo
Ileo reversed Mar 2004
Cancer free since then

gtownguy
Posts: 151
Joined: Thu Nov 22, 2012 7:57 pm
Location: Washington, DC

Re: Amitriptyline

Postby gtownguy » Wed Apr 02, 2014 7:44 pm

My oncologist prescribed 50 mg of Amitriptyline daily along with Neurontin for my neuropathy.
Sep 12 - dx rectal cancer - stage 3B - T3N1M0
Oct/Nov 12 - 6 wks daily radiation & Xeloda
4 Feb 13 - LAR w/ temp ileostomy
18 Mar 13 - install port
19 Mar - 02 Jul 13- FOLFOX chemo
23 Jul 13 - clean CT scans
26 Sep 13 - reverse ileo & remove port

User avatar
abuttigi
Posts: 669
Joined: Tue Feb 08, 2011 9:39 am
Location: SE Michigan

Re: Amitriptyline

Postby abuttigi » Wed Apr 02, 2014 10:03 pm

Amytriptyline is what is known as a "tricyclic antidepressant." These drugs act on a lot of different receptors, which is why they can be used for many things other than depression and psychosis. Don't let that scare you! What I will say is don't stop the medicine or even change the dose without speaking with your doctor. Since it works I'm many receptors, there could be side effects if you do!

Side note, I'm a medical student, so I don't want to give any medical advice, just clarification. If you've questions about the drug and how it's used, don't hesitate to ask your doc!

Angie
Daughter to George (64)
Dx'ed Jan '11 Stage IV CC liver and peritoneum, KRAS mutant
Folfox
Folfori, Avastin
SIRT
Aug '12- progression in liver, mets to lungs
Oct '12- mets to bone, Regorafenib
Nov '12- Hospice
12/10/12- Became my beautiful angel in heaven

sharpey92
Posts: 53
Joined: Tue Jan 21, 2014 10:22 am

Re: Amitriptyline

Postby sharpey92 » Thu Apr 03, 2014 5:32 am

Wow, quite literally overwelmed by all of your responses, thank you so much it is very much apprieciated

nicola smith
Posts: 1040
Joined: Thu Oct 07, 2010 9:06 am

Re: Amitriptyline

Postby nicola smith » Thu Apr 03, 2014 8:49 am

CRguy wrote:
nicola smith wrote:I was VERY surprised to learn that the drug was initially developed as an anti-psychotic :shock: .

and another fun fact ... amitriptyline was also used as a mellowing out prozac for kitties for cats with behavioural problems.



Cheers All
CRguy


Meow 8)
UC history
11/09: Dx, CEA 2.9
02/10: colectomy, temp ileo; pT3N1Mx
10/10: 12 Folfox6
03/11: jpouch
2010/11/12/13/14: 6 PET and/or CT's - NED
quarterly 03/2010- 03/2015: CEA range 0.8-1.3
03/2015: discharged to GP :D

User avatar
kellywin
Posts: 492
Joined: Wed Jan 23, 2013 4:46 pm
Location: Northern CA

Re: Amitriptyline

Postby kellywin » Thu Apr 03, 2014 12:05 pm

I took Amitriptyline for a couple of years when I was having really bad migraines all the time. It seemed to work. The only side effect I had was one they list, vivid dreams. Yes, it was pretty strange, the dreams would seem pretty real. I'd be talking to someone and have a thought back to a dream and think to myself, "did that really happen or was it a fream". Maybe like deja vu? Anyway, it seemed to work at the time.
Kelly, mom 14 yo girl
Dx 11/15/12 Rectal Cancer @ age 40
Stage IIIC
5.5 weeks Xeloda & Radiation - complete 2/5/13
Colectomy 3/12/13, 7 of 14 nodes positive - no ileo
4/24/13-8/20/13 - 5 rounds Xelox, 1 Xeloda only


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: No registered users and 358 guests