Postby wendysafrica » Fri Sep 12, 2008 2:30 pm
Another new article - seems the researchers are saying the same things we are...
Inoperable colorectal liver metastases: A declining entity?
European Journal of Cancer, 09/10/08
Garcea G et al. - In a review to report on available options in the treatment colorectal liver metastases (CLMs) that are considered unresectable by conventional evaluation, it was shown that a nihilistic attitude to the pt with seemingly inoperable liver metastases should be discouraged. Discussion of such pts at multi-disciplinary meetings is essential in order to plan and monitor treatments
Methods
Inclusion criteria were articles published in English-language journals reporting on either retrospective or prospective cohorts of pts undergoing treatment for conventionally inoperable CLM
Main outcome measures were survival, resectability rates, morbidity and mortality following treatment of the pts’ disease
Results
Improved chemotherapy regimens and other innovative treatments have opened up new options for pts and may even render conventionally inoperable disease resectable
Aim of treatment should be down-staging of metastases to achieve resectability, but other treatments such as ablation may be be used (either alone or in conjunction with resection)
38 yrs Apr 07 Colon resect/ovarian tumor out-CC+ovarian mets
2 wks later-rad hyster;FAP diag
06/07-09/07 XELOX/Avas;01/08 mets-abdo musc
01/08-06/08 XELOX/Avas;08/08-abdo mets surg
08/08-10/08-FOLFIRI/Erbitux
Surg 10/08-abdo mets surg
11/08 UFT/Rescuvolin