Stats..... so I was just thinking....

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dianetavegia
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Facebook Username: Diane Weldy Tavegia
Location: Villa Rica, Georgia

Stats..... so I was just thinking....

Postby dianetavegia » Sat Oct 12, 2013 9:04 am

We all know that Stats are always based on studies at least 5 years old. Just to verify, I googled/ bing'ed survival stats for colon cancer and see the reports are dated 2006 and 2007. Those studies were started 5 or more years prior to those papers being published. Let's say those studies were started in 2000.

PET scans have only recently become available to almost everyone. Actually, the PET scan was named invention of the year in 2000. That means all those people in the most current stats did NOT have PET scans to find cancer early. They did NOT have the newer chemos. Also, liver resection has become more common in the last 8 years BUT approximately only 20% of those with liver mets have HR today.
One report from 2004 said: 60% of colon cancer patients will have Liver metastases but only 10-20% of patients are candidates for surgery.
Again, no PET to find them early!

I believe the stats we will see in the next few years are going to show a much higher survival rate and much longer survival rates.

Thoughts?
Stage III cc surgery 1/7/09. 12 tx FOLFOX
Stage IV PET = 1.5cm liver met. HR 4/11/12

14 years since dx and 11 years post liver resection.
Pronounced CURED and discharged by onc

“O Lord my God, I cried out to You, And You healed me.” Psalms 30:2

Badass
Posts: 1171
Joined: Sun Jan 15, 2012 11:42 am

Re: Stats..... so I was just thinking....

Postby Badass » Sat Oct 12, 2013 9:27 am

I like your optimism...very uplifting!
R.C. 12/23/11 at age 52 T3N0M0
3/1/12 completed Xeloda and radiation
5/4/12 LAR & Ileostomy
6/7/12-10/4/12 6 rounds Xelox
11/27/12 Reversal
7/13/13 1 liver met
8/13 Met resection /hai pump
4/14 Chemo completed (Irinotecan/5fu/fudr in pump)

Val*pal
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Joined: Sun Feb 10, 2013 1:24 pm
Facebook Username: Valerie Barkus Kantner
Location: Metro Detroit, Michigan

Re: Stats..... so I was just thinking....

Postby Val*pal » Sat Oct 12, 2013 2:13 pm

Diane, I sincerely hope your theory is correct, and it may very well be. I've been amazed at the number of people who have had liver resections, and most seem to benefit. :D
DH dx'ed May '11, age 62
Jul '11: resection Stage IV
10/11: 6 mo Folfox
8/12:thyr canc, surg/tx
2/13: peri mets
2/13: Firi/Avas
6/13: Ok
8/13: break
10/13: Lung, peri, mets
10/13: Firi/Erb
1/14: Erb Fail; spread
5/14: Tx stopped
6/20/14: At rest

annalexandria
Posts: 684
Joined: Wed Sep 28, 2011 11:46 am
Location: Seattle, WA

Re: Stats..... so I was just thinking....

Postby annalexandria » Sat Oct 12, 2013 2:53 pm

PET scans really do make a big difference in outcomes, at least imo and based on my personal experience.
So this makes sense to me (and let's hope so).
Mom, librarian
Dx age 43, Sept. '09, Stage IV Carcinosarcoma of the colon
5 surgeries, 2009-2011:
colon/sm. bowel res., node removal, peritoneum, hysterectomy
FOLFOX/Avastin Feb.'10-Aug '10
Carbo-Taxol Dec. '10-Feb. 2011
NED since Dec. 2011.

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PGLGreg
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Joined: Sat Nov 04, 2006 12:38 am
Location: Waimanalo, HI

Re: Stats..... so I was just thinking....

Postby PGLGreg » Sat Oct 12, 2013 3:34 pm

This is something we definitely need -- future oriented stats. Why didn't anyone think of this before? We must get beyond this fixation on the past that makes us count survivors of the last five years, when what we should really be looking at is survivors of the next five years. Researchers, get your heads out of the sand!
Greg
stage 2a rectal cancer 11/05 at age 63
LAR 12/05 with adjuvant radiation+5FU,leucovorin 1-2/06
NED for 12 years, cured

mymom
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Joined: Fri Aug 12, 2011 11:07 pm
Location: Connecticut

Re: Stats..... so I was just thinking....

Postby mymom » Sat Oct 12, 2013 4:00 pm

I completely agree...no question about it. I know too many stage iv that are surviving longer than 5 years. I hope mom is one of them!
Stage 4 CC DX 5/11
colon/livr rsct 5/11(1 met)
Folfox July-11/11
NED to 5/12
New Primry BC-4/12,Stage 1
2 livermet 5/2012
Liver rsct,HAI 6/12,Folfiri
NED to 10/13,1 liver met,ablation, Folfiri
NED to 12/14, another spot
3/15 NED
Ablation 1 liver met 10/15
1/16-current NED
6/22- small spot liver again, ablation oct 2023

rp1954
Posts: 1855
Joined: Mon Jun 13, 2011 1:13 am

Re: Stats..... so I was just thinking....

Postby rp1954 » Sat Oct 12, 2013 5:28 pm

Early multimodal treatment is the key. The central problem is how to unleash existing, inexpensive technologies in a highly restricted marketplace with increasing regs. Also skillful avoidance of obsolete advice, opinion and "rules" is important.

Sequential blood tests and biomarkers are likely to "see" most new mets first. We just don't market available biomarker tests cheaply and efficiently, like $1-$2-$5 extra per marker, closer to incremental cost. We are billed as if old markers are rare and exhaustible heirlooms, instead of competitive pricing.
watchful, active researcher and caregiver for stage IVb/c CC. surgeries 4/10 sigmoid etc & 5/11 para-aortic LN cluster; 8 yrs immuno-Chemo for mCRC; now no chemo
most of 2010 Life Extension recommendations and possibilities + more, some (much) higher, peaking ~2011-12, taper chemo to almost nothing mid 2018, IV C-->2021. Now supplements

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ziggymonster
Posts: 538
Joined: Tue Feb 05, 2013 3:23 pm
Location: California

Re: Stats..... so I was just thinking....

Postby ziggymonster » Sat Oct 12, 2013 5:53 pm

I totally agree....I think the stats are outdated and trying to play catch up. In the days when medicine was not making many advances the stats made more sense. But in the last 10 years so much is advancing in modern medicine.
DX advanced prostate cancer 2002
2014 still fighting mPca , failed surgery, radiation, hormone
DX Stage IIIa Rectal Cancer 12/12 1 of 12 nodes +
LAR permanent colostomy 1/13
Folfox 2/13 - 7/13 clear CT CEA 1.2
7/14 liver met chemo the resect in Oct
6/15 2 pos lung mets watching for now

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Voxx66
Posts: 1844
Joined: Wed Jul 24, 2013 10:22 pm
Facebook Username: Michael Void Ward

Re: Stats..... so I was just thinking....

Postby Voxx66 » Sat Oct 12, 2013 6:20 pm

I think this is very true. The research oncologist I see has mentioned this numerous times. So yes, I think optimism has a well grounded basis in fact in this case.
DX and resect 10/2012 age 46
Stage IIa CRC
liver mets both lobes 8/2013
CEA 28
FOLFOX + Avastin 8/26/13 3 rounds
Folfox only 3 rds + rd 8
platelets low round 7,9,10 5FU only
1/14 CEA 1.0 y90
5fu
10/14 mets lung and peri
1/15 Folfiri

justin case
Posts: 4269
Joined: Sun Sep 04, 2011 8:26 am
Location: Katy, Texas

Re: Stats..... so I was just thinking....

Postby justin case » Sat Oct 12, 2013 6:49 pm

Hi Diane,
My doc was adamant about PETs, I had 4 before I ever had a CT. I am hopeful that most of the stats are wrong. I cannot believe in this computer age, that more recent stats are not available, in fact, up to the minute :roll:
Warm regards,
Michael
7/11 diagnosed Stage 2 colon and rectal cancer
chemo/rad
lar/temp ilio
Reversal & port removal
21 round of chemo Folfox 9tx, 5fu 12 tx
Last treatment July 2012

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WorriedWife
Posts: 1125
Joined: Tue Jul 24, 2012 5:41 pm

Re: Stats..... so I was just thinking....

Postby WorriedWife » Sun Oct 13, 2013 2:22 am

Hi Diane! I totally agree with you. I stopped using Google about 6 months after my hubby's dx because it became way too depressing and it's not anything close to what I was reading in the forums. I would rather discuss with real people, in real time than some dated chart and percentage somewhere that they aren't keeping up with. As we know among all of the people who get this horrid disease, everyone's outcome/treatment reaction is SO totally different. I've read for hours and hours in forums and articles in which I don't believe I've come across two of the same. The stats are just an old average and I don't pay attention to them because everyone is just so, so different. I've seen people with stage 2 advance to stage 4 and pass within a year and then I've seen stage 4 patients live for 15 years ...and more. I truly dislike outdated stats! Don't Google!! :D
Hubby
CC Stg. 2b
Dx 6/12
surgery & reconnect
opted out Folfox
Pet Scan Aug NED
abscess/fistula for over a year
ongoing Dec 2013
Praying for each and every one of you

Lisahopes
Posts: 328
Joined: Wed Oct 17, 2012 2:09 pm

Re: Stats..... so I was just thinking....

Postby Lisahopes » Sun Oct 13, 2013 1:49 pm

I hope you are right although the oncolologists don't seem to follow this thinking. If you are not resectable and Stage IV, I am not sure if much has changed in the past five years. The PET scans did not help my mom, who was diagnosed for the second time at Stage IV ( although all previous scans didn't show anything for almost 5 years after her Stage II diagnosis). Maybe we were just unlucky. I wish that a test were discovered that revealed tiny cancer molecules before scans could. I think that that would be a turning point.
Daughter to Mom, 65, Stage IV with mets to liver, lungs and peri.
Dx 2006, Stage II.
Regular check October 2011, Stage IV established.
She has had Oxi, Folfox and Xeloda, now Avastin.
Progression.
Mom died on April 5th 2013.

robinkaye
Posts: 374
Joined: Fri Nov 11, 2011 10:03 am

Re: Stats..... so I was just thinking....

Postby robinkaye » Mon Oct 14, 2013 12:40 pm

Lisa, I think the circulating tumor cell test does just that, still relatively new, not a lot of doctors using it regularly.
Just google circulating tumor cell if you're interested in reading more. Agra with you though, without curtive nothing much has changed. The PET is great for identifying problem spots while still hopefully respectable. The workhorse of chemo has been around since the fifties. We need more research in immunotherapies, nano technologies, bio markers and a whole lot more of things that I can't pronounce.
Husband has RC Stage IIIC
Chemorad 9/28-11/07
2 rounds FOLFOX to get rid of iliac LN
LAR Surgery 1/17 ileostomy
presacral abscess 2/1 - 3/27
FOLFOX began 4/5 - 6/15
another presacral abscess 6/30-8/10
Reversal 9/11
10/15 fistula with drain


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