I had my second opinion with doctors at the University of Chicago last week. I grilled them on the erbitux/avastin issue. They basically concurred with my doctor that, because I am stage III and have no distant metasteses, there is no reason for me to risk any of the potential side effects of these particular drugs in a clinical trial.
But they agreed that if I were stage IV, these would both be extremely promising drugs to try, especially given my age, general health, and so on. So it sounds like (given that fact that your brother is a year older than me), it'll be a good thing for him to try. I'm sure his doctor has told him the side effects of each drug and what warning signs to watch for. But if not let me know and I'll ask the doctors at UC to tell me more detailed information to post for you. There are side effects and you do have to be monitored very carefully for certain things on either of those drugs.
I start my chemo Thursday. I'll be thinking about you and your brother and wishing you both well. Be sure to let me know how his progress goes.
Best Wishes, Chet