Moving forward with a clinical trial

[sandrichelle]

Hi guys,

I just wanted to see if you guys had any insight, opinions, good or bad regarding the trial I am about to start. I am really hopeful that this may work for me

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic or Colorectal Cancer
http://ClinicalTrials.gov/show/NCT01053013


I so value you guys opinions!!

Michelle

[Felicia]

I think it's interesting! So they just put the cancer beads into your abdomen? Do I have that right? Looks like this one is open regardless of mutations.

Did they give you any idea on side effects you can expect?

Thanks for sharing.
Felicia

[Bev G]

WIshing you all success with this trial! You know all your friends here are with you in spirit, hoping and praying for the best, and anxiously awaiting GREAT news on results! Thanks for being a pioneer!

xoxox

Bev

[sandrichelle]

I think it's interesting! So they just put the cancer beads into your abdomen? Do I have that right? Looks like this one is open regardless of mutations.

Did they give you any idea on side effects you can expect?

Thanks for sharing.
Felicia

Felicia yes and regarding side effects some have reported some abdominal cramping but nothing long term and they have been doing it in humans for 7 years now.

[annalexandria]

Good luck, Michelle! It sounds like it's got a lot of possibility, so I hope it has great results for you. Big hugs coming your way~AA

[sandrichelle]

Thanks guys, I have my consult and screening on Monday! I will keep you posted

[Guinevere]

Good luck and I'm praying it successful!

God bless ~
Guinevere

[Val*pal]

How do they place the beads in the abdomen?

[sandrichelle]

The beads are placed in the abdomen via laproscopic surgery.

[skypup]

Have you read the following?

http://healthinfoispower.wordpress.com/ ... al-trials/ (a good overview. There are additional links in the bibliography you might want to track down.)

http://meeting.ascopubs.org/cgi/content ... 3594?rss=1 (this reports on the results of the phase 1 trial)

http://meeting.ascopubs.org/cgi/content ... 3594?rss=1 (from Nature, gives some report of the animal trials)

http://cancerres.aacrjournals.org/content/71/3/716.long (academic article, lots of info, much technical)

http://cancerres.aacrjournals.org/content/71/3/725.long (another academic article)

Looks very interesting, and not dangerous. Can't wait to hear how it goes and wishing you the best of luck!

[sandrichelle]

Skypup,

Some I have, some I have not and some I just really don't understand

Thanks!!! Much appreciated!

[sandrichelle]

Hi guys,
Just wanted to stop in and give you a quick update on my treatment. Not much to tell at this point except my cea did drop from 415 to 290 which is significant and promising. The procedure itself was realativly easy, only issue being pain control post surgery as I have been on so much medication it's hard to cover pain now, I have to take a lot! I have one spot in my butt bone, not a bone met but in the soft tissue that has been the culprit of most of my pain, well we are radiating it so I am slowly tapering off of the pain meds. Will keep you posted!
Thanks
Michelle

[usopen]

That's great Michelle. Nice drop in CEA.
While I was in Ny a few weeks ago, I realized I would be right across the street from where Dr. Smith's office is located.
We had made arrangements a few days before, to talk about the trial. I really liked Dr. Smith.
For now we decided to go forward with another plan with the local onc, and see what happens, but I am still very excited with his research. ( i have ascites, and Dr. Smith said that could affect healing even at the incision site of the beads. So on hold......but said stay in touch.
I am very, very, happy for you.

[skypup]

Hi guys,
Just wanted to stop in and give you a quick update on my treatment. Not much to tell at this point except my cea did drop from 415 to 290 which is significant and promising. The procedure itself was realativly easy, only issue being pain control post surgery as I have been on so much medication it's hard to cover pain now, I have to take a lot! I have one spot in my butt bone, not a bone met but in the soft tissue that has been the culprit of most of my pain, well we are radiating it so I am slowly tapering off of the pain meds. Will keep you posted!
Thanks
Michelle

Yay for the great drop in CEA! Thanks for the update. Wishing you continued success!!!

[Phuong]

Nice drop! Wishing you continued success. ((hugs))