green tea, turmeric, selenium, and aspirin

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pabl
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Joined: Thu Mar 25, 2010 9:41 am

green tea, turmeric, selenium, and aspirin

Postby pabl » Sun Jun 17, 2012 11:46 pm

A new food supplement from Israel targets colon and rectal cancer, as well as ulcerative colitis and other bowel diseases. The product, which has yet to hit the world market, is called Coltect. It is a combination of green tea polyphenols, curcumin powder from the turmeric root and the trace mineral selenium. Its effects were described at a recent oncology meeting and it is the subject of two clinical trials.

Results were presented at the 2010 American Society for Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. The authors, from Tel Aviv Sourasky Medical Center, tried Coltect alone or combined with a common drug, 5-aminosalicylic acid (5-ASA), in cell line and animal models of colon cancer.

Depending on the dose, there was up to an 83 percent inhibition of cancer cell growth using Coltect. In the animal model, the combination of Coltect and the drug 5-ASA reduced the number of precancerous lesions from 66.5 in the control group to 20 in the group that received both agents. The authors concluded that Coltect “can be administered as a chemopreventive regimen to prevent” colorectal cancer.

While waiting for Coltect to hit the world market, one might consider taking a combination of green tea polyphenols, turmeric (with its key ingredient, curcumin) and Brazil nuts (a good source of selenium–use the kind that you have to shell yourself).

As for 5-ASA, it is not available without a prescription. But it is a derivative of salicylic acid and is chemically similar to aspirin. A 2003 journal article concluded: “Preclinical, observational, and clinical data consistently show that non-steroidal anti-inflammatory drugs (NSAIDs)—particularly aspirin—reduce colorectal carcinogenesis” (Hawk and Vine, 2003). So you might ask your doctor about taking a baby aspirin (81 mg) along with the anticancer food components.

Colon cancer afflicts over 100,000 Americans each year. Perhaps some of these cases could be prevented by the judicious use of anticancer foods, supplements and drugs, all of which are readily available. The toxicity of such agents is low and the cost of all together is less than a dollar a day.

References:

http://clinicaltrials.gov/ct2/show/NCT00793130

http://biopromedical.com/Coltect.html

http://www.asco.org/ASCOv2/Meetings/Abs ... actID=1745

Hawk ET, Viner JL. Aspirin: still learning about the wonder drug. Gut. 2003;52(11):1535-1536.
RC 8 '09 at 45 y/o
Stage 3, 2 nodes
9 '09 rad and xel.
2 '10 resect, temp. ileo
3 '10 started 8 rounds Folfox, finished 6.
9 '10 ileo reverse
CT Scan---missed a 2 mm lung met (Jan '11)
Grew to 1 cm till yr. ct scan---VATS (Jan '12)
NED

pabl
Posts: 185
Joined: Thu Mar 25, 2010 9:41 am

Re: green tea, turmeric, selenium, and aspirin

Postby pabl » Sun Jun 17, 2012 11:48 pm

I didn't write the above article---Ralph W. Moss Phd. did.
Pam
RC 8 '09 at 45 y/o
Stage 3, 2 nodes
9 '09 rad and xel.
2 '10 resect, temp. ileo
3 '10 started 8 rounds Folfox, finished 6.
9 '10 ileo reverse
CT Scan---missed a 2 mm lung met (Jan '11)
Grew to 1 cm till yr. ct scan---VATS (Jan '12)
NED

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Gaelen
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Location: CNY
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Re: green tea, turmeric, selenium, and aspirin

Postby Gaelen » Mon Jun 18, 2012 12:45 am

Soo, basically, these guys have drawn CRC prevention conclusions for this concoction without ever having tested it long-term in a double-blind controlled clinical trial in humans (animal models aren't the same kind of design.)

I'd be very careful, especially while on chemo, about adding ANY supplement or combo of natural ingredients designed to mimic the supplement, with that sketchy a profile. You don't have even the percentages of each component with which to construct a supplement facsimile.
Be in harmony with your expectations. - Life Out Loud
4/04: dx'd @48 StageIV RectalCA w/9 liver mets. 8 chemos, 4 surgeries, last remission 34 mos.
2/11 recurrence R lung, spinal bone mets - chemo, RFA lung mets
4/12 stopped treatment

pog451
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Re: green tea, turmeric, selenium, and aspirin

Postby pog451 » Mon Jun 18, 2012 2:26 am

1) It works on rats, all that data is for rats and rodents only
2) No studies to show it works on humans
3) One study started in 2009 doesnt seem to have published any results

My money is on the manufacturers aiming to make a bomb before the study shows ineffectiveness or inconclusiveness.
09.11 Dx @ 46, uT3uN1M0 G2
11.11 radio+Xeloda
01.12 LAR
03.12 Xeloda
09.12 Liver mets, 2 LN
09.12 Folfox+Avastin
02.13 Resection
04.13 Folfox & Avastin
11.13 Local recurrence
02-07.14 FOLFIRINOX
08.14 Re-rediation
Left us 28.05.2015

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kimmercans
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Re: green tea, turmeric, selenium, and aspirin

Postby kimmercans » Mon Jun 18, 2012 7:00 am

Yeah for the uprising "medical food" industry! I think it is fantastic that companies are seriously considering marketing supplements as medicine.

I heard Israel was about ready to launch a huge industry in medical foods. Looks like that might happen.

Can't rx in the United States without FDA approval....so it will have to undergo some human trials. Look forward to those results.

Kim
Kimberly Age 54 Diagnosed at 44
Dx'd rectal ca 10/12/09
LAR,TME 10/14/2009 Stage 2a
Opted out of Folfox.
4/19/12 CT scan clear NED CEA<0.5
10/2019 still NED
Taking curcumin, Celebrex, vitamin d, digestive enzymes, bio identical hormone replacement.
2015 to present. Stopped all surveillance. Living life one glorious day at a time.

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MonaL
Posts: 479
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Re: green tea, turmeric, selenium, and aspirin

Postby MonaL » Mon Jun 18, 2012 4:39 pm

I believe that there is evidence for compounds of most of those things independently, but form and bioavailability of course is a factor.
Dad, stage IV CC, mets to liver, 2007-2008
surgery, Xelox, and IP-6
NED summer 2009
surveillance stopped summer 2014, due to age
died 1/2018 at age 88, from Parkinson's and respiratory infection
(Parkinson's triggered by one of his cancer surgeries and/or chemo)

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Jimswife
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Re: green tea, turmeric, selenium, and aspirin

Postby Jimswife » Mon Jun 18, 2012 4:57 pm

We take all these daily among others :)
Victoria , Wife to Jim age 43 dx oct 2011
Stage 3 cc with 2 out of 21 positive lymph nodes
Folfox starts nov 11-may 12
All scans and bloods since surgery confirm no evidence of disease
Hoping to stay ned forever .... Fingers crossed !!!!!!!

Rick7
Posts: 322
Joined: Sun Mar 15, 2009 5:38 pm
Location: Los Angeles

Re: green tea, turmeric, selenium, and aspirin

Postby Rick7 » Mon Jun 18, 2012 8:35 pm

Pabl,
Thank you for posting this and please keep us updated if you are following this.
I already take a Baby Aspirin and and Tumeric daily. I also try to drink green tea daily. I will have to check into Selenium.

Thanks again,
Rick
CC DX 1-7-09 at age 40 - Stage IV, T4-N1-M1
Surgery 1-16-09 - Folfox6 Feb-Aug 2009
Clear scans - PET/CT 9-09, CT 3-10, CT 9-10
Head MRI 3-11, CT 9-11
Head CT 2-12, PET/CT 9-12

pog451
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Facebook Username: andrew.morgan

Re: green tea, turmeric, selenium, and aspirin

Postby pog451 » Tue Jun 19, 2012 3:38 am

kimmercans wrote:I think it is fantastic that companies are seriously considering marketing supplements as medicine.


Sorry, im not sure I get this. You think its fantastic that companies try and market possibly useless supplements at a massive mark-up to people desperate to grab at any straws when there is little or no evidence that these supplements are healthy, let alone "medicine"? Am I missing something? (yeah actually, Im missing making a killing repackaging common or garden herbs and spices as "medicine")

Sorry again, sounds like a snake-oil rip-off to me.

Believe me, as soon as anyone has even believable anecdotal evidence that any of this stuff helps, Ill be buying it by the kilo, but until then...
09.11 Dx @ 46, uT3uN1M0 G2
11.11 radio+Xeloda
01.12 LAR
03.12 Xeloda
09.12 Liver mets, 2 LN
09.12 Folfox+Avastin
02.13 Resection
04.13 Folfox & Avastin
11.13 Local recurrence
02-07.14 FOLFIRINOX
08.14 Re-rediation
Left us 28.05.2015


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