Canadianmom wrote:Well it's good, but I've been hoping that the new research would have shown greater five year + prognosis'. Thanks for posting, I'll have to read the full article!
Surgical resection outperforms radiofrequency ablation in single liver-only spread from colorectal cancer
Posted by Kate Murphy on May 18th, 2006
When colorectal cancer has spread to the liver only and nowhere else, removal or destruction of the liver tumors offers the best chance for a long term survival or cure....
Tumors recurred in the liver more often after RFA (37%) than hepatic resection (5%).
After 5 years, more patients who had surgery were free of liver mets (92% vs. 60%).
After 5 years, 50% of the surgical group were cancer-free compared to none in the RFA group.
After 5 years, 71% who had surgery were alive compared to 27% who had RFA.
Thomas A. Aloia, MD and his team at M.D. Anderson reported their results in the May 2006 Archives of Surgery. They concluded:
The survival rate following HR (hepatic resection) of solitary colorectal liver metastasis exceeds 70% at 5 years. Radiofrequency ablation for solitary metastasis is associated with a markedly higher LR (local recurrence) rate and shorter recurrence-free and overall survival rates compared with HR, even when small lesions (3 cm) are considered. Every method should be considered to achieve resection of solitary colorectal liver metastasis, including referral to a specialty center, extended hepatectomy, and chemotherapy
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