Maia wrote:Steph20021 wrote: I'm told once I get off folfiri I won't be able to go back on, and it's keeping me stable but for an abdo wall met.
Why would be that? Because the healthcare system won't cover it, as per Canadian guidelines? Because, scientifically, there is no reason. In fact, I see in a FB group for MSS-CRC-clinical-trials-only that people revisit Folfiri often, after being in one, or two, immuno trials, when they need it. Their oncs propose that. And some go back to it after being "failed it" (not just because they stopped to get into a trial).
(Just copying a message from yesterday: "Atezo/cobi did not work for me and with my infection my lungs Ct has got worse. Back on folfiri and looking for another trial.")
And you have trials that *include* Folfiri in the combo (just an example: https://clinicaltrials.gov/ct2/show/NCT02024607. BBI608 is not an immunotherapy but a cancer stem cell inhibitor, a pill.
Also, there are MSS patients that are getting Keytruda or Opdivo from the manufacturer, per recommendation of their oncs. One that I know, it 's getting it in combination with Folfiri (onc recomendation too). But this is in USA.
I'll ask my one this morning why that is, (I should have asked) but Im pretty sure it's related to our healthcare funding. And I agree I would probably be looking for a colon specialized oncologist in Toronto, I'll give it some thought out transferring my care. I liked having Toronto weigh in when I was with them for the period of Hipec, but once I had a post-hipec recurrence they dropped me like a hot potato because I wasn't eligible for another surgery. So now I don't have that extra Toronto Dr and opinion anymore. And I am definitely keeping a list of trials for when chemo starts failing me! Thanks Maia. I think it's incredible the support and info you provide for us all.