is 1.1 CEA considered high?

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gjsabmor
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Location: Dallas, Texas

is 1.1 CEA considered high?

Postby gjsabmor » Wed Jan 11, 2012 12:14 pm

Mom's CEA is up from 0.6 last month to 1.1 this month ... is this cause for concern? nobody on the team seems to think so but I am freaking out. She has one more Folfox treatment to go.
Mom diagnosed w/mCRC 27 June 2011
Currently in treatment (Folfox + Avastin)
Histologically low-grade adenocarcinoma
2 out of 15 lymph nodes positive

nicola smith
Posts: 1040
Joined: Thu Oct 07, 2010 9:06 am

Re: is 1.1 CEA considered high?

Postby nicola smith » Wed Jan 11, 2012 12:19 pm

nope it's not high at all. in fact well within normal range.

edited to add: My signature lists the results of all my CEA tests at three month intervals (more or less) starting with diagnosis (2.9)
Last edited by nicola smith on Fri Jan 13, 2012 3:00 pm, edited 1 time in total.
UC history
11/09: Dx, CEA 2.9
02/10: colectomy, temp ileo; pT3N1Mx
10/10: 12 Folfox6
03/11: jpouch
2010/11/12/13/14: 6 PET and/or CT's - NED
quarterly 03/2010- 03/2015: CEA range 0.8-1.3
03/2015: discharged to GP :D

Grace14
Posts: 418
Joined: Mon Oct 24, 2011 7:42 pm

Re: is 1.1 CEA considered high?

Postby Grace14 » Wed Jan 11, 2012 12:21 pm

Oh my god not at all in fact my cea was at 1.0 at the highest it's now back to .06. I think the normal is 3.5 so anything over that I might be concerned but dont be concerned over 1.1 that is still actually very low!!
Diag Stage 2a R/C April 2010 at 38
Rad/chemo 6 weeks
Apr surgery July 2010
Folfox 4 months
Jan appendix removed
Feb diag papillary thyroid cancer no treatments stage1
Ned so far!!!
Mother of 4 boys 21 18 11 8

nbrandt
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Re: is 1.1 CEA considered high?

Postby nbrandt » Wed Jan 11, 2012 12:24 pm

Just to help you feel reassured. CEA does rise during treatment when cancer cells are dying or so I have read here on this board. Having my CEA done this Friday . The Oncologist said if the CEA Test rise is 6 -10 then time to retest and then CTscan. Most who use the CEA as a good test will chime in soon and also let you know this is not considered high for those who use this as an indicator for recurrence.
NBrandt
DXCCT3N2aMx 5/20LN
Folfox10/10-4/11
Scan 10-13-10,4-4-11,7-4-11,9-22-11,4-9-12,9-24-12,10-1-13,4-9-14,9-17-14,9-10-15,9-15-17NED,
CEA 1. Pre .6 7-4-11 .7 9-22-11 .6
1-13-12 .9 4-9-12 .7 9-24-12 .6 1-4-13 .8 10-1-13 .8 4-9-14 .7 9-17-15.8
Courage, Hope, Health

weisssoccermom
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Location: Pacific NW

Re: is 1.1 CEA considered high?

Postby weisssoccermom » Wed Jan 11, 2012 1:44 pm

I'll chime in as well - that level is perfectly normal.

My CEA has bounced all over the place - from 0.5 at dx to 1.9 at it's highest and everything in between. It can be scary when you see it rise but just keep in mind that it's like anything else that fluctuates (weight, bp, temp). It's NORMAL for the level to go up and down slightly and the variation that you're talking about is miniscule.
Dx 6/22/2006 IIA rectal cancer
6 wks rad/Xeloda -finished 9/06
1st attempt transanal excision 11/06
11/17/06 XELOX 1 cycle
5 months Xeloda only Dec '06 - April '07
10+ blood clots, 1 DVT 1/07
transanal excision 4/20/07 path-NO CANCER CELLS!
NED now and forever!
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hannahw
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Re: is 1.1 CEA considered high?

Postby hannahw » Wed Jan 11, 2012 1:56 pm

As others have said, 1.1 is totally fine. I've heard CEA described as pass/fail - anything under 6 is considered passing. But there are exceptions, like if you smoke, or have the flu, or your liver is going crazy after chemo - your CEA might be over 6 and it's not a sign of the cancer doing anything. That's why your doc is looking for trends. A steadily rising CEA might be cause for some concern.

CEA is only a small piece of the puzzle. It's a protein that some GI tumors produce and others don't. If your cancer produces CEA, it might be a good indicator for you. If you're like my Dad - his cancer has never produced CEA - your CEA may never go above 2 regardless of what your cancer is doing.

When my Dad was first diagnosed, I sweated every value/measurement of every test. When he was in the ICU I would sit watching his pulse, blood pressure and oxygen levels for hours, feeling anxious over the slightest (totally normal) bobbles. Your body isn't static. It's like a city, always moving, changing, building up, tearing down, etc. Values will fluxuate and it's totally normal. It's easier said than done, but try not to live on the test rollercoaster. As my Dad's onc says "Scan to live, don't live to scan." (Or in this case, blood draw.)
Daughter of Dad with Stage IV CC

sadysue
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Joined: Tue Aug 02, 2011 6:59 pm
Location: Charleston, TN

Re: is 1.1 CEA considered high?

Postby sadysue » Wed Jan 11, 2012 1:58 pm

Wow, I've never seen a CEA that low in anyone on chemo. That's a great number IMO and you should be VERY pleased. Mine is 2.6 and I am thrilled! For most folks, anything below 4.0 is considered normal. Good luck.
Mary Ann
Rectal dx 4/2011 (Stage 3B - T3N1M0)
5FU/Rad - daily/6 wks ending 6/2011
Surgery 8/19/2011
Finished 8 rounds Folfox 2/2012
Ileo reverse and port out 3/2012
NED

gjsabmor
Posts: 174
Joined: Tue Sep 06, 2011 4:26 pm
Location: Dallas, Texas

Re: is 1.1 CEA considered high?

Postby gjsabmor » Wed Jan 11, 2012 4:14 pm

I appreciate your responses ... you've been an amazing support group for me throughout this journey and have yet again put my mind to ease.
Mom diagnosed w/mCRC 27 June 2011
Currently in treatment (Folfox + Avastin)
Histologically low-grade adenocarcinoma
2 out of 15 lymph nodes positive

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Patience
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Joined: Fri Dec 09, 2011 10:26 am

Re: is 1.1 CEA considered high?

Postby Patience » Wed Jan 11, 2012 4:31 pm

My husband's is approx 250. :(
"Sweet dreams till sunbeams find you.
Sweet dreams that leave all worries behind you."

SkiFletch
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Location: Buffalo, NY

Re: is 1.1 CEA considered high?

Postby SkiFletch » Wed Jan 11, 2012 5:13 pm

Mine went 5.6 preop, 1.1 chemo start, <0.5 after round 4, 1.0 after round 8, <0.5 ever since. Totally not a big deal for CEA to bump around a bit during chemo. It's almost normal ;)
11/13/09 5cm Stage IV 9/25 lymph nodes w/2cm peritoneal met at 29 YoA
12/15/09 LA right hemi-colectomy
6/16/10 Folfox FINISHED
8/10/10 Prophylactic HIPEC
10/9/10 got Married :D
Still NED and living life to the fullest

"Can any one of you by worrying add a single hour to your life."

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wwroam
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Re: is 1.1 CEA considered high?

Postby wwroam » Wed Jan 11, 2012 5:24 pm

1.1 is quite low.
For the first 2 years after chemo mine was stuck around 3.5 with little fluctuation. Then it started to rise reaching 4.9 in June last year. My oncologist showed no concern so I didn't either. In December it was back to 3.5. Go figure.
Stage 3a DX 25/06/07
Folfox complete 30/01/08
7 years NED
Port scheduled for removal 8/02/10 Gone.
PSA .54 No prostate problems
Diagnosed Type 2 Diabetic
SO diagnosed CC Stage IV Liver Mets 23/03/15

Toby57
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Location: Texas

Re: is 1.1 CEA considered high?

Postby Toby57 » Wed Jan 11, 2012 6:00 pm

I was never tested for CEA during chemo, the Onc said the chemo fluctuate the number. He said normal, and I have a printout which says 0.0 to 7.2 is normal for non smokers. Different labs use different methods, my pre-surgery CEA was 3.8 and normal for non-smokers is 3.0, and that was a hospital lab that uses their own methods, different than the cancer center. They should give you a printout that shows the normal range . For my center, I have to stay below 7.2. It is confusing.
54/ Father of 4 . Married to a loving wife
Dx cc Oct.2010/ colon resection,40cm of colon removed.
Stage 3B , 4/37 nodes.
T3N2A, kras Wild
Completed 12x Folfox , June 2011.
Clear Scans June & Dec, 2011, CEA normal.
Live , give , and forgive.

Grace14
Posts: 418
Joined: Mon Oct 24, 2011 7:42 pm

Re: is 1.1 CEA considered high?

Postby Grace14 » Wed Jan 11, 2012 6:19 pm

Wow I feel like I'm the only one with a high cea before diagnosis!! Mine was 26 its been below 1.0 ever since!! Does anyone else know what there's was before diagnosis? Just curious!!
Diag Stage 2a R/C April 2010 at 38
Rad/chemo 6 weeks
Apr surgery July 2010
Folfox 4 months
Jan appendix removed
Feb diag papillary thyroid cancer no treatments stage1
Ned so far!!!
Mother of 4 boys 21 18 11 8

Surroundedbylove
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Joined: Tue Dec 16, 2008 6:43 am
Location: Seattle

Re: is 1.1 CEA considered high?

Postby Surroundedbylove » Wed Jan 11, 2012 6:53 pm

For some people CEA is a marker and for other's it isn't. We've seen lots of people over the years with high CEA at diagnosis and others with normal. For me, it isn't a marker and even at diagnosis it was below 1. I wish it were a marker for me because it could help docs gauge things from blood tests - but it just isn't.

So, don't worry if it is a marker or if it isn't. Some tumors express it and others don't - doesn't mean anything in terms of the cancer from what I understand.
Surroundedbylove

Rectal Cancer @ 43, '08
Clinical: T3,N2a,MX (IIIB)
6 wks XELOX & radiation
LAR, colonic j-pouch, & temp ileo '09
Surgical: ypT3,ypN0,ypMX (0 of 20 nodes)
FOLFOX; XELOX
Ileo Takedown ‘09
LARS for 10 years before learning it is finally being studied
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shmurciakova
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Location: Sugar Grove, VA

Re: is 1.1 CEA considered high?

Postby shmurciakova » Wed Jan 11, 2012 6:54 pm

Patience, My oncologist says she's seen patients w/ CEA in the thousands, so don't despair! The important thing is what the number is doing over time. If it is going down then that is generally taken as a good sign. If it is continually going up then that might mean something is going on.
-Susan H.
diagnosed at 31 in 2002, Stage IV
Sigmoid colectomy - 6 mos 5-FU/Leukovorin
liver resection - 6 rounds XELIRI (xeloda/irinotecan)
lung wedge resection Oct. 2004 - no chemo
NED!!


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