Avastin side affect

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Avastin side affect

Postby mymom » Mon Nov 21, 2011 5:42 pm

Hi all

My mother has been on chemo FOLFOX since July. They tried to introduce Avastin several weeks ago with the FOLFOX but she had some face swelling so they stopped it. They said they may try again separately from FOLFOX after her rounds are over (she has 4 more) or possibly introduce on the off weeks with FOLFOX. A few questions:

1. Has anyone had this reaction (face swelling- no problems breathing) with Avastin?
2. If so, what did the onc do?
3. Has anyone had Avastin alone after FOLFOX?
4. Has anyone had Avastin on the off weeks?

thanks in advance
Stage 4 CC DX 5/11
colon/livr rsct 5/11(1 met)
Folfox July-11/11
NED to 5/12
New Primry BC-4/12,Stage 1
2 livermet 5/2012
Liver rsct,HAI 6/12,Folfiri
NED to 10/13,1 liver met,ablation, Folfiri
NED to 12/14, another spot
3/15 NED
Ablation 1 liver met 10/15
1/16-current NED

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Re: Avastin side affect

Postby Nickmark59 » Mon Nov 21, 2011 8:29 pm

I had a similar problem with oxilaplatin where my face swelled and jaw locked and i was witched to folfox later on my onc found out and it was caused by it being pushed to fast. wonder if same thing can happen with avastin?
CRC- IV 7-th yr Survivor -5 rectal tumors 1 bleeding with mets to liver
Rad. 36 treat.
with 6 Chemo 2-Ox.- 4 Fol.
surgery 15 hrs to resect colon and liver- Feb 08
follow up 6 chemo Folfox

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Re: Avastin side affect

Postby deb1223 » Mon Nov 21, 2011 8:40 pm

I've been on Avastin alone since March of this year. The only problem I've had is a sore that simply will not heal. I've even had a strong dose of antibotics and thought it was cleared up. However, after my last dose of Avastin it has flared up again. I'm thinking about calling for my CEA count and if it is still stable postponing my next treatment to see if I can't get this sore to heal. Other than that no problems, it's a heck of a lot easier than folfox.
52 Yr. old Female, DX July 2010
Stage IV CC, 21 mets to liver, 1 to lungs
12 Rounds Folfox
To date no surgeries
Enlarged spleen
Been on Avastin only since Mar. 2011

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Location: Canada

Re: Avastin side affect

Postby triciah » Mon Nov 21, 2011 8:59 pm

I had swelling but it was with Vectibix. Avastin gave me blood clots and sinus/nose damage.
Dx Stage IV 12/09
Ileostomy 1/10
Rad 2/10
Surgery 5/10
FOLFOX + Avastin 8/10-11/10
Iri 4/11 and 6/11
Vect 8/11-9/11
Multiple lung mets
03/12: swollen lymph nodes, possible liver met, 3 bone mets
"I am His and He is mine"

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Re: Avastin side affect

Postby Guinevere » Mon Nov 21, 2011 9:45 pm

I was on Avastin for 4 treatments and developed a severe pain in my left jaw that radiated to my ear. I thought after being off of it for a month, it would get better but it hasn't.
Hrt atk - Feb 11
CRC4 DX - Apr 11
APR liver rsct, procto - Jul 11
Folfox/Avastin - Sep 11
Xeliri - Nov 11
Iritux - Jun 12
Break - Jan - Mar 13
Iritux - Mar 13
Stivarga - Aug 13
Folfiri - Oct 13
Exhausted treatment options - May 14

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