Fever with Folfox

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Joined: Sat Apr 04, 2009 9:00 am

Fever with Folfox

Postby frickletsx3 » Fri Feb 18, 2011 2:31 pm

I've been looking back at some of the other posts about fever with Folfox and it seems to be related to bacteria in the port.

I have had FOLFOX in the past without problems but have recently restarted it. After first dose I had 103 temp and lots of chills. Was started on antibiotics yet blood cultures came back negative. Then for second round of Folfox same thing happened, only faster and worse. Again negative blood cultures, no blockage in the port.

Was wondering if anyone else has had this reaction to Folox without there being an obvious cause (infection). IF so did anything work to offset it, like premeds? am very worried about the next infusion.
43 Dx 1/09 stage IV extensive carcinomatosis
7/09 rt liver lobectomy
1/11 liver and node met restarted Folfox
4/11 liver resection
mom to 17 yo twins and 16 yo

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Joined: Fri Oct 08, 2010 11:53 pm
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Re: Fever with Folfox

Postby RixInPhx » Fri Feb 18, 2011 7:05 pm

Just finished Folfox 5 weeks ago.
I had minor fever/chill spells several times on about day 3.
Not severe enough (less than 100F) to be immediately concerned about, nor to initiate cultures at next round.

I haven't found anything in the literature of any of the chemicals related to fever/chills, other than to be wary of infection.
M 61, Dx 6/10 CRC st 4, unknown primary CEA 843
2 kg peritoneal mass, met to skull; no surgery
Various regimens of all CRC chemo drugs
Mets to lung 8/11 CEA 135
Folfiri/Erb/Ava 12/11 CEA 320
No progression 5/12 CEA 192

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Joined: Thu Dec 17, 2009 6:19 pm
Location: Columbia Falls, Mt

Re: Fever with Folfox

Postby airic » Fri Feb 18, 2011 7:22 pm

I had fevers and hot flashes. As high as 101. I took a couple of asprin and rested fever gone. I think it is just a side effect. When I snow skiied after a dose I would get fevers, I knew I would get one and treated it before it got bad. I did 12 rounds of Flofox 6. No problems since I have been off treatment.
Stage IV Colon Cancer
8 inches of Colon removed 11-13-09
Lymph Nodes removed 11-13-09
Liver peice removed 11-13-09
Colosotmy Bag 11-17-09
Start Chomo FLOFOX6 Jan. 4th 2010

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Posts: 178
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Location: Ontario

Re: Fever with Folfox

Postby LeeT » Fri Feb 18, 2011 7:32 pm

I was wondering if this was a side effect. I had a fever of 101- 102 and chills on the day of pump disconnect...ended up going to the hospital for blood tests...WBC was fine. Now I know for next time.
Proud mamma of Rhys and wifey to Grant
Dx 29 April Stage IV mCRC cancer with mets on liver
18/05- Started FOLFIRI with Avastin

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