Question regarding genetic conditions and CRC

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nurtrk18
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Joined: Tue Aug 17, 2010 8:34 pm
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Question regarding genetic conditions and CRC

Postby nurtrk18 » Sun Aug 29, 2010 1:31 pm

Does anyone have experience with E-cadherin? I'm questioning this diagnosis for my sister since she was diagnosed with CRC at age 29 (signet cell adenocarcinome) and my father passed away at age 56 with gastric cancer (signet cell adenocarcinoma). They tested her for the most common mutations for HNPCC which were negative.
Thank you!!
Sister - dx with Stage III signet cell CRC in 04/10 @ age 29
07/10 - completed 5 weeks of radiation & 5FU
10/10 - attempted tumor removal but found mets to
PC and omentum - now Stage IV
10/10 - started Folfox & Avastin
05/11 - possible HIPEC

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