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by rp1954
Fri Dec 15, 2023 11:08 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IVC and weekly FOLFIRI
Replies: 12
Views: 3203

Re: IVC and weekly FOLFIRI

For those who wish to maintain a high Vitamin C level, there is a new alternative. There is a supplement that repairs the liver so that it can convert sugar into Vitamin C. Until we see qualified, independent technical reports of vitamin C blood level profiles over time (pharmacokinetics) for oral ...
by rp1954
Fri Dec 15, 2023 11:46 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: 5FU and folic acid
Replies: 9
Views: 2981

Re: 5FU and folic acid

In the US, it is any grain or grain product IIRC. Have to be careful, almost paranoid in countries that fortify with folic acid. For my wife it was really multi B complex pills with folic acid rather than bread, gravy and cereal bowls. For about half the population genetics, it's any folic acid with...
by rp1954
Fri Dec 15, 2023 11:41 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IVC and weekly FOLFIRI
Replies: 12
Views: 3203

Re: IVC and weekly FOLFIRI

All the cancer patients here that I am aware of have, have capped their single day IVC dosage at 1.5 grams per kg or lower. More vitamin C per day is possible but tedious to start with, and progressively more difficult physiologically on ion/electrolyte balances. One clinical study suggested that th...
by rp1954
Fri Dec 15, 2023 11:02 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: 5FU and folic acid
Replies: 9
Views: 2981

Re: 5FU and folic acid

Yes. 5FU - folic acid is the original analysis.
by rp1954
Fri Dec 15, 2023 1:02 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IVC and weekly FOLFIRI
Replies: 12
Views: 3203

Re: IVC and weekly FOLFIRI

Also my wife dropped down to 30 -35 grams per IV for a while and her AFP marker went exponential, with a 40-50 fold rise, until restoration at 60-65 grams knocked AFP back down. Investigators who have tracked multiple cancer markers in patients in/near remssion have noticed various markers elevating...
by rp1954
Fri Dec 15, 2023 12:43 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IVC and weekly FOLFIRI
Replies: 12
Views: 3203

Re: IVC and weekly FOLFIRI

While we continue working on trials, I’m going to restart chemo - but given the Gilbert’s difficulties we’re going to do a weekly 5FU bolus, a smaller dose of irinotecan, and 3-weekly bevacizumab. Idea is to be able to maintain more stable drug levels with less toxic doses, and tweak dosing more of...
by rp1954
Mon Dec 11, 2023 8:07 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: How Refined Sugar Fuels Cancer
Replies: 8
Views: 3209

Re: How Refined Sugar Fuels Cancer

One's susceptibility to cancer is impacted by all kinds of factors - genetics, diet and nutrition, immune function, inflammation(s), ROS and other pathologies, and gut biome. We are still early in the improvement phases. The biome type theory can even be extended by chemical reactor kinetics, based ...
by rp1954
Sat Dec 09, 2023 10:07 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Aspirin may benefit cancer treatments (Prevents metastasis)
Replies: 5
Views: 4261

Re: Aspirin may benefit cancer treatments (Prevents metastasis)

... I agree there are many benefits of aspirin. I believe the benefits of aspirin outweigh the bleeding risks as long as someone doesn't have a bleeding disorder. Again, its always best to consult your oncologist. Based on my research, aspirin is more beneficial to CRC patients with a PI3K mutation...
by rp1954
Sat Dec 09, 2023 6:09 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: How many of you take daily dose aspirin?
Replies: 11
Views: 8512

Re: How many of you take daily dose aspirin?

What brand of mk4 do you use? I have found it almost impossible to find. Yes the market offerings in the US for vK2 pills over 5 mg of menatetrenone(MK4) seem to have reduced by at least two vitamin brand sources, perhaps squeezed by a single(?) primary supplier in China and generic supplement comp...
by rp1954
Tue Dec 05, 2023 11:14 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Trial update - ATRIUM (ATG-018)
Replies: 30
Views: 16032

Re: Trial update - ATRIUM (ATG-018)

Rock_Robster wrote:...after nearly a MONTH of screening) as my LDH was too high.

Sorry about that.
What LDH did they consider too high (also normal lab range/UL=?) and how many days/weeks after IV vitamin C was it drawn?
by rp1954
Tue Nov 28, 2023 11:55 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: FDA investigates 'serious risk' of secondary cancer following CAR-T treatment
Replies: 2
Views: 3294

Re: FDA investigates 'serious risk' of secondary cancer following CAR-T treatment

Big pharma overstating benefits and ignoring side effects and negative data. Who would of thought? However, I'm not sure that it even counts as a Faustian bargain for 2nd and 3rd line patients, rather "just" a reduction in benefits, unless the long term effect is even uglier than the origi...
by rp1954
Sun Nov 26, 2023 5:00 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: How many of you take daily dose aspirin?
Replies: 11
Views: 8512

Re: How many of you take daily dose aspirin?

I've taken low dose aspirin since the 1980s n (and less excess calcium). Niacin is an anti-inflammatory for 1-2 major cytokines and in a pinch could drop my total cholesterol and raise my HDL dramatically. use collagen forming supplements that may help strength blood vessels, maintain vascular inte...
by rp1954
Tue Nov 21, 2023 6:12 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: How many of you take daily dose aspirin?
Replies: 11
Views: 8512

Re: How many of you take daily dose aspirin?

I've taken low dose aspirin since the 1980s since there are at least two prior generations of fatal colon cancer in my lineage. Also early large polyps in a sibling, 6 at 35 yo. Also 3-4 generations of early heart attacks in the guys across the male lines, late 40s-60s. In the 1980s, I found I could...
by rp1954
Thu Nov 16, 2023 1:24 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Elevated liver enzymes!
Replies: 6
Views: 3026

Re: Elevated liver enzymes!

Obviously each person has particular chemical tolerances. Whether your partner's liver elevation was primed by Folfox and cumulative dose-damage or he is particularly more sensitive to Folfiri, I don't know. As a matter of choices, we chose no to low liver elevation and lower CBC impairment for long...
by rp1954
Tue Nov 14, 2023 5:11 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Any Thought On NK Cell Therapy?
Replies: 6
Views: 2961

Re: Any Thought On NK Cell Therapy?

their PBT is very expensive, but you can always get that in the US). Japan, Korea, China and Europe have done some work with He4, C12, O16 ion beams. Might be an area of review for specialized situations, with different RBE and toxicity than protons, which were not considered especially effective f...

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