Hi there. Forgive me for the unsolicited advice, but since no one has mentioned it on this thread- Have you considered HAI (hepatic pump) treatment? I'm not sure what your physical situation is, but for people with mets limited to the liver, it can be an excellent option for many. I won't swamp you ...

I went to MSK for the pump install (and colon primary resection), didn't have Dr K as my onc, but a colleague of hers who was fantastic (as were the colon and liver surgeons I had.) I was lucky to live less than 4 hours away, but knowing what I now know, I would have gladly taken a plane if I needed...

Yes, it's the Oxaliplatin in FOLFOX that could cause permanent neuropathy, though it's rare to get permanent debilitative neuropathy. In my case, I had 12 txs of FOLFOX, the last 3 were slightly reduced. Frankly, knowing what I know now, I may only have done about 8 or so txs of OX, and 2 reduced. A...

Sorry you had to join our world, but you've already gotten some great advice from folks here, and hopefully this site will be useful in helping you and your husband plan and cope with treatment. Just two things I wanted to add... PLEASE consider the possibility of HAI / hepatic pump if your husband'...

I used to take a BCM-95 curcumin formulation, since I believe I read that it was the formulation that was used in one or more studies on colon cancer effectiveness, with high bioavailability. I personally took one pill per day (not sure the mgs), though who knows what the ideal dose would be. I shou...

I would humbly suggest looking into HAI / hepatic pump if your metastases are liver-limited. It involves a hockey-puck sized pump being implanted in your abdomen, which gives highly concentrated chemo (usually FUDR), but only to your liver. It can be (and usually is) given with systemic chemo during...

Hi, sorry about your news. Just wanted to concur with kandj...from what I hear, Dr K and MSK will only treat with HAI if the cancer mets are limited to the liver - though maybe also in a few rare cases where there is extremely limited involvement elsewhere. In my case, I had a couple portal lymph no...

Chemo (not sure if it was the systemic, but more likely it was HAI) fried my bile ducts too. I had a big blockage (bilirubin shot up to double digits, got the jaundice, itching etc.). They fixed it with a stent, but those stents all eventually get clogged up again, it's just a matter of how soon. Af...

FOLFIRI/CPT-11 is often very effective, and in many cases FOLFIRI is used instead of FOLFOX as first line treatment. And mitomycin C can also be helpful, though likely to a lesser degree. (Personally I'm intrigued by metformin too, but I digress.) In any case, the point I wanted to make here is that...

It seems like your dad has a few other things going on that might make it a little more difficult surgery than mine. But for my part, I had no real issues with recovery whatsoever, I was very lucky. It was essentially the same recovery as when they initially resected my colon primary; they cut open ...

What can be done varies widely between people due to location of blockage, anatomy, current health situation, and any number of other factors. But...in my case, my team at Sloan Kettering implanted a couple bile duct stents over the past couple years due to blockage/degradation of bile ducts, and cl...

I had gradually increasing AST, ALT and ALP which started pretty much around the time I first started systemic chemo, and maybe slightly accelerated 6 months later when I first started HAI/FUDR treatment. As you are probably well aware, HAI can cause permanent liver damage, which is why they follow ...

Skypup, I have utmost respect for you, you've fought the battle for so long, and done it with such grace. And obviously you have met this straight on and done plenty of research. So I'll be (perhaps overly) straightforward. At this point, given the varied locations of your mets, and what you've trie...

Sorry you had to join the club. Needless to say, stage IV is a shocking diagnosis when you first get it, and will likely take some time to sink in. Just know that it is not always the death sentence that way too many oncologists will tell you it is. Many people here are living long term with - or ev...

Just an fyi, Peter Trayhurn was referring to David Morris.