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by rachel2017
Sun Dec 17, 2017 11:07 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TIL Immunotherapy at NCI
Replies: 635
Views: 256974

Re: TIL Immunotherapy at NCI

The G12D mutation results in an amino acid substitution at position 12 in KRAS, from a glycine (G) to an aspartic acid (D). https://www.mycancergenome.org/content/disease/colorectal-cancer/kras/34/ So yes, G12D. Thanks a lot! I called NCI and a lady gave me this trial contact information. I was a l...
by rachel2017
Sun Dec 17, 2017 5:26 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TIL Immunotherapy at NCI
Replies: 635
Views: 256974

Re: TIL Immunotherapy at NCI

For most patients, adoptive cell transfer starts with an operation at the National Cancer Institute. By removing one of your tumors, we are able to find and grow the immune cells that live there, known as tumor-infiltrating lymphocytes or TIL. We will grow and study TIL from your tumor in our labs....
by rachel2017
Sun Dec 17, 2017 5:22 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TIL Immunotherapy at NCI
Replies: 635
Views: 256974

Re: TIL Immunotherapy at NCI

Hey, Mike, Thanks for your explanation. Now I have better understanding about Dr Jimmy Yang’s trial. My question is my mom have KRAS mutation: Gly12Asp. What kind of mutation is it? Is this differencing from G12D? Thanks in advanced!
Rachel

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