I'd get the booster AND chemo, but delaying chemo for a week or two is not a deal breaker. It has happened to many if not most of us at some point in 12 rounds of folfox. Worst case scenario your antibodies are only somewhat boosted. I just read that in fact they are talking about a potential second...
I experienced significant hair thinning on FOLFOX, maybe 30%? But it was kind of even, not falling out in clumps and leaving bare spots. They told me that it would typically slow down or stop at about the 8th cycle, and that is roughly what I experienced. I was beginning to wonder if I was going to ...
This is fascinating. I hope this approach works for you. (And others. I had vaguely heard of efforts to sensitize non-MSI tumors to immunotherapy using radiation.)
Please, do, keep us informed. Keeping all appendages crossed for you!
If the MSI test that they did was "equivocal" they could do another test with a different tissue sample, and they could use the same approach or the alternate approach to testing. In my opinion, there is no excuse to accept an "equivocal" finding. They should persevere until the...
Equivocal MSS/MSI? That's a new one on me. Seems to generally be a result of testing failure because of poor sample or something like that. Can you delve into that more? What was equivocal about it? Not sure about dMMR/pMMR? Something else? MSS with high TMB maybe? Being responsive to immunotherapy ...
Given that mucinous tumors don't typically respond well to conventional chemotherapy, genetic testing at an earlier stage seems wise to me. My oncologist has been having genetic testing done on all of his stage 3 patients for several years. It doesn't have to be Foundation One.
Even though you are MSS you may still have mutations that significantly affect your treatment, so you should still get it. And, not to confuse the matter but important, if your tumor mutation burden is 12 or so, you may still be eligible for immunotherapy. In addition, there are trials going on that...
To my knowledge, hysterectomy would only be under consideration if she has Lynch, or actual uterine cancer. Lynch cannot be diagnosed without genetic testing of both the tumor and her blood. I'd ask the doctor why he is recommending it. I would definitely get a second opinion before undergoing a hys...
If you want information about lung mets, the Lungston "neighborhood" of Colontown--a large, private community on Facebook--would be a good place to look. Colontown is a superb resource for support and science-based information, and posts are visible only to members.
That's an easy question to answer: nothing automatically means anything. :lol: Seriously, there are many things that can cause CEA to rise. If CEA is a good marker for her, a certain level of concern may be warranted, but it is my understanding that a trend is more significant than a single reading....