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by Maia
Fri Sep 15, 2017 8:29 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: My mom's journey is over
Replies: 31
Views: 7711

Re: My mom's journey is over

Lmighty... I saw your message days ago and I've been sharing your pain. I know, feel, how you made everything possible for you mom, with a realistic outlook, looking after he quality of life also and first. You maybe perceived how close I've felt to you in this past months. I also lost my dear frien...
by Maia
Mon Sep 04, 2017 10:02 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Rectal case from Hong Kong (UPDATE: Lung Met, NRAS MUTATED, FOLFOX+Avastin)
Replies: 52
Views: 9896

Re: Rectal case from Hong Kong (UPDATE: Lung Met, KRAS MUTATED, PLZ HELP!)

The mutation is important to know because it has immediate clinical impact --treat with a certain drug or not. But it is not really a mutation that usually makes the cancer more aggressive. On the other hand, being KRAS practically exclude her from having other mutation that many times can be more a...
by Maia
Mon Sep 04, 2017 7:38 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Rectal case from Hong Kong (UPDATE: Lung Met, NRAS MUTATED, FOLFOX+Avastin)
Replies: 52
Views: 9896

Re: Rectal case from Hong Kong (UPDATE: Lung Met, KRAS MUTATED, PLZ HELP!)

Hi, Mercy In a rush here, so replying your PM in the open forum, in case it helps others --My mum's genetic test shows KRAS mutation. Practically speaking, I know there are certain kinds of targeted drugs are not useful on her right now. With a KRAS mutation, Erbitux and Vectibix can't be used. Ther...
by Maia
Sun Sep 03, 2017 8:34 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Rectal cancer (Stage 3A) diagnosed late June 2017
Replies: 1760
Views: 496182

Re: Rectal cancer (Stage 3A) diagnosed late June 2017

but I would suggest getting yourself some pads. That way you can stick them to your underpants and they will stay in place. Plus, they are disposable. My husband thought I was nuts when I suggested it for him when he had a really bad boil lanced in his nether region, but he appreciated it when it s...
by Maia
Sun Sep 03, 2017 6:32 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Grouseman
Replies: 5
Views: 2142

Re: Grouseman

I'm here, T. Sending my best!
by Maia
Sat Sep 02, 2017 4:25 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: More chemo?
Replies: 36
Views: 8054

Re: More chemo?

Congrats, Basil!!! This if fantastic!! Kudos to your doc and here to the trial protocol to become SOC.
by Maia
Sat Sep 02, 2017 4:21 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Positive News
Replies: 7
Views: 2176

Re: Positive News

Congratulations!! So happy that such innovative combination is working for you. Keep going, every day there are steps forward a durable response, even a cure.
by Maia
Sat Sep 02, 2017 4:08 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IMMUNO combo trial for Stage II and higher rectal ca working :)
Replies: 7
Views: 1988

Re: IMMUNO combo trial for Stage II and higher rectal ca working :)

I never get tired of being in awe at your ''journey'', as our CRGuy says, my dear fellow zombie fighter.
Hey, slowly, we are getting down more zombies in the last years, uh. 8)
by Maia
Fri Sep 01, 2017 10:39 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: IMMUNO combo trial for Stage II and higher rectal ca working :)
Replies: 7
Views: 1988

IMMUNO combo trial for Stage II and higher rectal ca working :)

Oregon August 31, 2017 Good news from trial NCT02688712, for Stage II rectal cancer receiving first treatment, to illustrate why and how clinical trials shouldn't be considered something to try after everything failed. * Chemoradiation+ Xeloda or 5-Fu + IMMUNOTHERAPY (TGFβ Type I Receptor Inhibitor ...
by Maia
Wed Aug 30, 2017 11:21 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TECENTRIQ (atezolizumab) + COTELLIC (cobimetinib) for Stage IV, starting 11/7/2017
Replies: 31
Views: 10149

Re: TECENTRIQ (atezolizumab) + COTELLIC (cobimetinib) for Stage IV, starting 11/7/2017

I hope your mom continue improving!
LMighty, in case you missed her: you have a fellow from HK looking after her mom, too: viewtopic.php?f=1&t=58637 viewtopic.php?f=1&t=58739
by Maia
Wed Aug 30, 2017 11:17 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Stage4 Mum with Multiple Lung Mets
Replies: 16
Views: 3723

Re: Stage4 Mum with Multiple Lung Mets

I saw your med from your signature. Keytruda is only available in very few private clinics in HK. In HK, you have an ongoing trial with a drug that is the Novartis equivalent of Keytruda, PDR001, also an anti PD-1, *combined* with other immunotherapy. Your mom is probably MSS, and Keytruda or other...
by Maia
Sat Aug 26, 2017 5:36 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TECENTRIQ (atezolizumab) + COTELLIC (cobimetinib) for Stage IV, starting 11/7/2017
Replies: 31
Views: 10149

Re: TECENTRIQ (atezolizumab) + COTELLIC (cobimetinib) for Stage IV, starting 11/7/2017

Update #7: The past weeks were full of ups and downs. The good news was that the chest + abdomen CT scan confirmed that no blood clot is present, and that peritoneal met is indeterminate, at worst minimal despite months of ascites accumulation. The bad news though was that our onc thinks that my mo...
by Maia
Thu Aug 24, 2017 4:47 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: More chemo?
Replies: 36
Views: 8054

Re: More chemo?

I'd love the CRC immunizations I think. But you have to be stage 4 to get into that trial (DFCI Oncologist told me that). It takes three months to make the vaccine as it's custom for every patient and I can't imagine what it costs. If you are referring to the trial I was mentioning, # NCT02960594, ...

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