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by Jacques
Fri Dec 16, 2022 3:00 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda dosing
Replies: 18
Views: 10955

Re: Xeloda dosing

How far back do your various inflammation series go? e.g. CRP, ESR, fibrinogen, D-dimer, IL6, IL8, ceruloplasmin, ferritin Hi Rob - When you had the problem with DVTs, did they test you for systemic inflammation? If so, which markers did they use? Any of these ... ? D-DIMER = https://www.mayoclinic...
by Jacques
Thu Dec 15, 2022 1:47 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Post Surgery
Replies: 4
Views: 5427

Re: Post Surgery

Liz - Welcome to our forum! If you are interested in obtaining informational support here, I think it would be a good idea to collect copies of all of your medical reports done so far. These reports contain the information that defines your diagnosis and staging, and they will form the basis for you...
by Jacques
Tue Dec 13, 2022 11:07 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda dosing
Replies: 18
Views: 10955

Re: Xeloda dosing

Hi Rob - Thanks for posting your long update above. It helps clarify the last line in your signature. I had another look at your signature and I annotated a copy of it by stratifying the events by year (see below). The red highlights refer to the middle two years, which are basically the COVID pande...
by Jacques
Tue Dec 13, 2022 2:05 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Tips for taking Questran (cholestyramine) and Imodium (loperamide)
Replies: 1
Views: 3858

Re: Tips for taking Questran (cholestyramine) and Imodium (loperamide)

... My gastroenterologist mentioned that as we tweak the cholestyramine dosage, we might need to add Imodium to the mix as well. Does anyone here also take both? I understand that other medications generally have to be taken either 1 hour before or 4 hours after taking cholestyramine, so I'm curiou...
by Jacques
Tue Dec 13, 2022 1:01 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda dosing
Replies: 18
Views: 10955

Some treatments for Xeloda (capecitabine) side effects

... I’ve just finished the first 2 weeks and have had to skip a few doses (as he suggested) due to side effects - mainly early appearance of early stage hand/foot syndrome, and early mouth ulcers . So I expect I’ll get a dose reduction next cycle. Wondering where most people end up with their dosag...
by Jacques
Mon Dec 12, 2022 2:32 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: PET/CT tomorrow
Replies: 69
Views: 43325

Re: PET/CT tomorrow

beach sunrise wrote:... Sognatera still showing neg. Will redo on the 15th to make sure. I asked about the test not being good at detecting cancer with lung mets maybe. Answer was they will get back with me. Haven't got a response yet.

Did you mean Signatera™ ?
by Jacques
Sun Dec 11, 2022 3:24 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda dosing
Replies: 18
Views: 10955

Re: Xeloda dosing

⋅  Initial Diagnosis and Staging, October 25, 2018 Initial diagnosis: Stage IV-A --Rectal Cancer with 4 mets to liver. Liver mets considered resectable. Primary tumor considered resectable as an ultra low anterior resection (ULAR). The two surgeries planned as sequential: liver surgery fi...
by Jacques
Sat Dec 10, 2022 9:56 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Phase 1 trial.
Replies: 33
Views: 25615

Re: Phase 1 trial.

I’ve started the phase 1 trial today for 2 drugs [ BGB-A425 and Tislelizumab ?] . One binds to CEA producing cells and the other to an immune cell. My dose was the 2nd lowest at 15 mg weekly and will stay at that level for 8 weeks then a CT will evaluate if it’s been effective. If the Mets have pro...
by Jacques
Fri Dec 09, 2022 1:59 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Recently diagnosed
Replies: 16
Views: 8461

Re: folic - FU

rp1954 wrote:... Most solo Xeloda patients reduce or eliminate HFS problems with IV vitamin C twice a week...

High Dose IV Vitamin C
https://www.acpm.net/medical-services/high-dose-iv-vitamin-c/
by Jacques
Tue Dec 06, 2022 5:22 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: CT scan - any value?
Replies: 6
Views: 2528

Re: CT scan - any value?

In my opinion, you should get the CT scan this week. The risk is minimal, and you will get good information from it. Also, I think you should probably do something about your constipation problem. This is because you would not want to end up in the ER some week-end and then be forced to have an emer...
by Jacques
Tue Dec 06, 2022 5:06 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: New here, seeking info/advice: 41yo stage 4 CRC, mets to 3 sites
Replies: 3
Views: 2240

Re: New here, seeking info/advice: 41yo stage 4 CRC, mets to 3 sites

Partner to Male, now 43yo; (which province?) , Canada MSS; KRAS (G12A), PIK3CA, APC, more 02/21 - stage 4 CRC, rectal primary; mets to liver, lung, peritoneum; colostomy; palliative chemo only 03/21 - Folfiri+Avastin 04/21 - pulmonary emboli, blood thinner (which one?) ; filgrastim for neutropenia ...
by Jacques
Mon Dec 05, 2022 8:46 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: New to the forum
Replies: 13
Views: 3298

Re: New to the forum

Hi nmorgen - Here are some links to the primary documents of interest for your DH's immunotherapy regimen, followed by a few of my comments: ⋅  2014 : Start of first Phase 2 clinical trial of Opdivo+Yervoy for mCRC "Checkmate-142", Phase 2 clinical trial, 6 cohorts (treatment arm...
by Jacques
Mon Dec 05, 2022 4:25 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Happy holidays to all
Replies: 7
Views: 3369

Re: Happy holidays to all

Happy holidays to everyone and blessings to all ! This is now the second week of the four-week Advent season for Christmas. If anyone is interested, there is a devotional calendar published by a Colon Club member that covers these 25 days of Advent. If so, just let me know and I'll try to find the r...
by Jacques
Mon Dec 05, 2022 3:38 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: PET/CT tomorrow
Replies: 69
Views: 43325

Re: PET/CT tomorrow

... Does anyone know if you have to show a vax card to cross the border into England then Germany? Here is where you can get up-to-date COVID information on travel from England to Germany: https://www.kayak.com/travel-restrictions/germany?origin=GB However, be sure to note the following disclaimer ...
by Jacques
Mon Dec 05, 2022 1:30 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: New to the forum
Replies: 13
Views: 3298

Re: New to the forum

...I guess I am hoping that there will be others that I can talk to and get advice from. Thanks nmorgen - I think I understand your husband's situation now, at least in part. If you're interested, I could share some thoughts, but these would only be thoughts and would not qualify as "advice&qu...

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