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by GrouseMan
Mon Jan 25, 2021 10:40 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Wnt pathway
Replies: 4
Views: 350

Re: Wnt pathway

In addition to this, members Maia and Grouseman, separately, posted a dozen or more messages referencing this topic also in the 2014 timeframe. I'll have to go back and review what Maia and I said on this topic 6+ years ago. Wnt is not an easy drug target from what I remember. A couple of other mem...
by GrouseMan
Wed Jan 20, 2021 5:03 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Avastin and Avascular necrosis
Replies: 2
Views: 357

Re: Avastin and Avascular necrosis

Yes - My wife was on it for almost 4 years. But She was not diagnosed with this side effect. She had some pretty bad lower back pain going on for about 6 months towards the end of her life. MRI etc didn't really sort out that back pain. Pretty inconclusive as to where it was coming from. I believe i...
by GrouseMan
Fri Jan 15, 2021 4:48 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: DK37 Science Posts List
Replies: 18
Views: 45764

Re: DK37 Science Posts List

OK - Its been a while since I posted something in this topic. Generally - I like to showcase some research that is probably directly applicable to the readers of this forum. I certainly don't have as good access to the journals and things that DK37 had or I for that matter 15 years ago. But I still ...
by GrouseMan
Wed Jan 13, 2021 12:48 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: How easy is it to differentiate between benign liver spots and small mets on a CT scan?
Replies: 4
Views: 818

Re: How easy is it to differentiate between benign liver spots and small mets on a CT scan?

Imaging is not a very good means of differentiating one thing from another and it really takes specialists with a good eye to even see the very subtle changes in between scans. One would like to have the same radiologist compare the scans and hopefully not be the first or last of the day that they d...
by GrouseMan
Fri Jan 08, 2021 4:45 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: VEGF and TGF beta 1
Replies: 5
Views: 697

Re: VEGF and TGF beta 1

I wouldn't disparage Avastin too much. I am surprised that you were not put on it at the time you had FOLFOX. Its side effects really are very minor when compared to the Oxaliplatin, 5-FU or Irinotecan. When My wife was on Irinotecan, Avastin and Erbitux without the 5-FU she thought that was a piece...
by GrouseMan
Tue Dec 29, 2020 1:58 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: COVID and Vitamin D
Replies: 5
Views: 1108

Re: COVID and Vitamin D

I have been taking High dose Vit D for a few years now. I don't spend a lot of time outdoors and when I do I cover up. I started taking it when a friend said it helped her with some joint and or bone pain. I had also read that its has a potential to be protective against colon cancer. I don't know i...
by GrouseMan
Thu Dec 10, 2020 11:47 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: 1 year clear from stage IV
Replies: 22
Views: 4118

Re: 1 year clear from stage IV

Congratulations :!: :!: :!: Good news is good news and should be celebrated.

GrouseMan
by GrouseMan
Fri Nov 27, 2020 2:15 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: HAPPY THANKSGIVING!
Replies: 3
Views: 578

Re: HAPPY THANKSGIVING!

Yes - I had a very nice Thanksgiving holiday with my dearly departed wife's sister and her husband. I am grateful that they still include me as a member of the family especially seeing as I am dating another woman now who happens to be a breast cancer survivor (a mutual friend introduced us). Unfort...
by GrouseMan
Mon Oct 26, 2020 10:32 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Support Group
Replies: 4
Views: 906

Re: Support Group

Green Tea wrote:Friday noon, Zoom support group:

https://cancernavigatorsga.org/2020/08/zoom/


Might be useful to know the time zone? There are 24 Noons around the world :D Can't tell which time zone you or Lmanners31 are in or if in the same. This is a good start.

Good luck!

GrouseMan
by GrouseMan
Thu Oct 22, 2020 11:51 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Support Group
Replies: 4
Views: 906

Re: Support Group

At the top of the forum topics there are several that are pined to the top. One is titled: SUPPORT GROUPS - Local Nationwide Please List Yours! http://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=31958 You might want to take a look at that and see if there are groups or links to online g...
by GrouseMan
Wed Sep 02, 2020 11:03 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: My first Avastin treatment.
Replies: 9
Views: 2445

Re: My first Avastin treatment.

It has a tendency to raise ones blood pressure. Usually they prescribe a BP med. My wife was on an ACE inhibitor (Lisinopril) at the lowest dose while on Avastin. Her BP was always low because she was very athletic and was a runner. So the worst side effect from Avastin was the blood streaks in the ...
by GrouseMan
Tue May 26, 2020 11:17 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Colon Club mentioned in the Miami Herald
Replies: 3
Views: 833

Re: Colon Club mentioned in the Miami Herald

Thank you for sharing Grouseman. I hope you are doing well. I am doing OK. I started dating a breast cancer survivor, and that has made things easier. This is a rough time of year for me. 3rd anniversary of my wife's passing coming up. This Covod-19 stuff is bothersome, but for the most part doesn'...
by GrouseMan
Fri May 22, 2020 10:31 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Colon Club mentioned in the Miami Herald
Replies: 3
Views: 833

Colon Club mentioned in the Miami Herald

FYI an interesting article was run in the Miami Herald in which the Colon Club was mentioned.

Here is the Link:

https://www.miamiherald.com/living/heal ... 89351.html

This turned up in one of my news feeds.

Enjoy

GrouseMan
by GrouseMan
Fri Apr 17, 2020 1:39 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Hello - I'm new here
Replies: 4
Views: 1214

Re: Hello - I'm new here

Good for you! My wife worked full time as an engineer up until 4 months before she passed away. She tolerated Chemo very well and was never really on a break from it. Would leave the infusion center and drive to work afterwards. Although she never had Folfiri and avastin she did the other combinatio...
by GrouseMan
Fri Apr 17, 2020 1:16 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: should I send this letter to my husband's onc (or not)?
Replies: 7
Views: 1460

Re: should I send this letter to my husband's onc (or not)?

Well - you seem, to be pretty well informed. Perhaps better than your husbands oncologist on the face of things. BUT he does have the medical degree and my experience has been that many of these guys have an attitude when someone questions their knowledge. Its also possible that the oncologist has o...

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