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by lichens
Tue May 19, 2015 7:51 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: My new met shocked the doc
Replies: 4
Views: 1444

Re: My new met shocked the doc

Definitively push your onc to get you on denosumab shots. Multiple trials (see below) have shown it is much more effective than Zometa at preventing bone complications. http://news.cancerconnect.com/denosumab-more-effective-than-zometa-at-delaying-bone-complications/ http://www.ncbi.nlm.nih.gov/pubm...
by lichens
Tue May 19, 2015 12:04 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: My new met shocked the doc
Replies: 4
Views: 1444

Re: My new met shocked the doc

Bradyr, a past member who is no longer with us had multiple bone mets on his legs. Bone mets can usually be treated very effectively with radiotherapy. Here is a post where bradyr talked about his bone mets: http://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=8047&p=54470#p54470 If y...
by lichens
Tue Oct 21, 2014 2:52 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: TAS-102
Replies: 7
Views: 1641

Re: TAS-102

From the trial results, it looks like TAS-102 only offers marginal survival benefit very similar to that of regorafenib. TAS-102 http://www.onclive.com/web-exclusives/Fast-Track-Designation-Granted-to-TAS-102-in-mCRC N=800 2:1 ratio randomization OS (Overall Survival): 7.1 mos vs. 5.3 mos HR (Hazard...
by lichens
Tue Sep 30, 2014 3:56 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Camomile tea ?
Replies: 4
Views: 1618

Re: Camomile tea ?

The chemical compound that may have some anticancer properties in camomile tea, as well as in parsley and celery, is apigenin . http://en.wikipedia.org/wiki/Apigenin There are a couple of abstracts on NIH describing it: http://www.ncbi.nlm.nih.gov/pubmed/23485682 http://www.ncbi.nlm.nih.gov/pubmed/1...
by lichens
Tue Sep 16, 2014 3:28 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xilonix (MABp1) -on trial (update)
Replies: 19
Views: 9629

Re: Xilonix (MABp1) -on trial (update)

For those interested, there is a recently development for the trial involving Xilonix (see link below). XBiotech, the company behind the drug recently did an unexpected interim study and halted the trial. Results from the interim data were positive. It showed a statistically significant survival ben...
by lichens
Tue Sep 02, 2014 3:44 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Anti-CD47 antibody research update (link to trial)
Replies: 8
Views: 2006

Re: Anti-CD47 antibody research update

The trial is now listed on clinicaltrials.gov: http://clinicaltrials.gov/show/NCT02216409 Code name for the drug is Hu5F9-G4. Even though the trial is listed as recruiting, according to Stanford, the first group of participants have already been identified from current Stanford patients and they are...
by lichens
Wed Aug 20, 2014 2:02 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: BBI608 - Cancer Stem Cell Inhibitor
Replies: 2
Views: 1111

Re: BBI608 - Cancer Stem Cell Inhibitor

I just read an article in regard to BBI608 that I thought I should post here: http://www.fiercebiotech.com/story/phiii-flop-top-boston-cancer-stem-cell-program-batters-dainippon-sumitomo/2014-05-27 To summarize, phase 3 trial using BBI608 for CRC was stopped early due to a lack efficacy. This become...
by lichens
Tue Aug 19, 2014 1:06 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Anti-CD47 antibody research update (link to trial)
Replies: 8
Views: 2006

Re: Anti-CD47 antibody research update

It looks like the trial is finally starting up. Below is the latest information from Stanford on the trial: (8/15/14) Update on the anti-CD47 cancer therapy clinical trials The phase-1 clinical trial of the anti-CD47 antibody is designed to test its safety. The trial will accrue one patient per mont...
by lichens
Thu Aug 07, 2014 11:08 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Alternative and Integrative Treatment Discussion
Replies: 65
Views: 10759

Re: Alternative and Integrative Treatment Discussion

Dear All, I just verified current price of pien tze Huang. One box is 10tabs for HKD6,990. I only buy from Hong Kong. Father That sounds about right. I spoke to an acquaintance who works in the TCM field. Pien Tze Huang is roughly ¥550 CNY per tab (~$90 USD) in China, so you really shouldn't pay mo...
by lichens
Sat Aug 02, 2014 7:29 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Difficulty getting in Ipilimumab/ Nivolumab trials?
Replies: 10
Views: 1959

Re: Difficulty getting in Ipilimumab/ Nivolumab trials?

FYI this trial is designed with MSI+ patients in mind as BMS thinks Ipilimumab will have the most effect on those patients. If your husband is MSI+ he should have absolutely no problem getting into the trial. This trial also has an extremely small portion to test Nivolumab on patients who are not MS...
by lichens
Wed Jul 30, 2014 10:47 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Possible donor for BBQ Charity?
Replies: 17
Views: 1968

Re: Possible donor for BBQ Charity?

The message is most definitely a scam, email address is a dead give-away. A cursory search on the web led me to Sam Simon Foundation Facebook page https://www.facebook.com/pages/The-Sam-Simon-Foundation/63918477241 A July 20th posting on the page states: Scam emails are going around again claiming S...
by lichens
Wed Jul 30, 2014 9:49 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Anti-CD47 antibody research update (link to trial)
Replies: 8
Views: 2006

Re: Anti-CD47 antibody research update

Latest update on this subject (potential trial) from http://stemcell.stanford.edu/CD47/ (7/7/14) Update on the anti-CD47 cancer therapy clinical trials The phase-1 clinical trial of the anti-CD47 antibody is expected to begin this summer or in the early fall. This first phase is designed to test the...
by lichens
Mon Jul 28, 2014 11:41 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Epigenetic therapy - an emergent cancer treatment approach
Replies: 2
Views: 866

Epigenetic therapy - an emergent cancer treatment approach

Recently Maia was kind enough to share with me a lot of very interesting information about epigenetics. This is an exciting area in cancer research and clinical trials using this approach are starting to appear for treatment of solid tumors as can be seen in this trial ( http://clinicaltrials.gov/ct...
by lichens
Thu Jul 10, 2014 10:44 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: BBI608 - Cancer Stem Cell Inhibitor
Replies: 2
Views: 1111

BBI608 - Cancer Stem Cell Inhibitor

Some very interesting abstracts were presented during ASCO this year about BBI608. There are currently 2 clinical trials (a phase 2 and a phase 3 trial) using this drug for colorectal cancer. Since stem cells are naturally non-rapidly dividing and have the ability for DNA repair, they are resistant ...

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