I wonder about the possibility of tackling the liver first (perhaps an HAI pump, as someone mentioned) at Sloan, get them under control/eliminated, and then tackle the peritoneal mets, if possible. This is an absurd statement. No surgeon will undertake a liver resection with peritoneal mets as a ru...

More and more genetics is thought to be what determines patterns of spread. I read recently a study that posited lung as the more likely destination in Kras mutant patients, slightly more likely. Lymph node involvement - let's get clear on that one. Due to surgery a number of positive lymph nodes ma...

Yes what brownbagger and I had was a T3 tumor - intact and not locally advanced - and yet bleeding. And to note, I was stage 4 with a T3. In T4 the tumor has broken through the wall. It could be a very grim situation if it had spread locally and was bleeding and effusing. But Nicola you said it is s...

Firstly, what do people mean by 'bleeding tumor' ? Many people are diagnosed with blood in their stool. My primary tumor was described in path language as fulminant and on its image on my colonoscopy report blood was evident. I believe it was ulcerated as well. Yet I had very little evident blood in...

The word Gaelen is not at all Celtic but the LANGUAGE "Gaelic" is.... Galen was an ancient Greek physician of great influence who believed that cancer was a black bile substance that coarsed through the body - or something like that but the black bile was Galen's theory. Many subscribed to...

Indeed, Laurettas spoke my thoughts, that this was a metaphorical use of Jobs. Jobs, like the space age, represents the furthest in achievement that we, mankind, has gone... has come. Cancer research, among the least far. Jobs, too, was only human. He could succumb like the most healthy among us, to...

Jen, What the phleb-..... the blood taker thinks doesn't matter at all. Maybe she is not yet as mature as you are and freaked out by the idea it could happen to her - because she is young. A lot of para health professionals are not trained or experienced in the ways doctors and nurses are and have n...

Hey Diane,

You have shared some totally sensible stuff about this topic, too, and seem to be the walking text book case for solitary liver limited met resection.

Wow, can that be turned into a license plate or something ?! SLLMR!

F

No problem Lisa. Actually, in my case, I have never thought twice about my decision, either. I have gone over some of the chapters of my treatment, a lot, but not that. I know this sounds kind of petty, but I think it would be fair to say I have read just about everything on this question that's out...

I'm really loath to post on this question nowadays. Because what for me approaches medical advice MORE than anything I see on this board increasingly, is the stuff about chemo. Right now, there exists no standard of care for post-liver chemotherapy. There is no study evidence of any notable signific...

Yo Rick, be brave, be strong and all the things you are already - sixty times over.

Frances xx

Hi Beatrice, Zaltrap is the brand name for a new drug, Aflibercept, which is not a chemo drug. It is a "cousin" of Avastin, or Bevacizumab, a monoclonal antibody that targets a receptor that helps a tumor cell put down footing in an endothelial cell in the blood vessel, in its lining. As y...

Hi, Two of the oncologists agree - Folfiri equals second line. Adding Avastin is just to increase potency. It also has good efficacy in the lung. So two oncologists want second line chemo, an aggressive approach, and one wants to wait and see. They are not cross-comparing, so I don't see they are 'd...

Thanks again for posting these links. I can't help but see a revived interest in this growing due to the current status of research on immunotherapy - Laurettas has brought up some great stuff. It's interesting that Coley was a casualty of his times to the extent that his research got selected out i...

There has been a lot of newish research published on Avastin in the past year. It has been shown to have no use in the adjuvant setting - Traveler is right. It has not been shown to have benefit in a micro-metastatic setting. I must differ w my buddy Ski, here, to say that Avastin indeed has pre-sur...