zephyr wrote:

stevieb wrote:
My tumor had KRAS mutation G12D.

Hey Sophy!! I’m still in ADAPT also. Hopefully, for 3 more months and then I can get off if it!!



Thanks for posting and giving hope to another Stage IV with a KRAS mutation.

Same here. Congratulations! -John

Hi, Claudine, thanks much for your information about Onvansertib. I googled and it does sound very promising in the Phase 1b/2 clinical trial in KRAS-Mutated mCRC. https://pipelinereview.com/index.php/2020042874476/Small-Molecules/Onvansertib-Trial-in-KRAS-Mutated-Colorectal-Cancer-Demonstrates-Cons...

Hi, jep ... thanks much for your notes. As your husband is starting to use STIVARGA® (regorafenib), did your oncologist mention the immunotherapy drug Opdivo (Nivolumab)? The combination of the Rego +Nivo sounds like a promising treatment (for MSS) though Nivo is an off-label drug which would need t...

Hi, I am new to the forum and many messages posted in the forum are very helpful. I am starting Lonsurf + Avastin treatment next week after 22 cycles of FOLFIRI + Avastin with slight progression. I am also a little bit nervous for the new treatment. I would like to have your input on your treatment ...