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by emkaye
Mon Jul 16, 2018 3:19 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

Hi emkaye, There is an interesting article on colorectal carcinoma:pathological aspects. It says “adherence of other organs or structures at the tumor site does not necessarily qualify for T4b. Histologically, the adherent site may show only inflammatory changes, abscess formation and/or fibrosis, ...
by emkaye
Tue Jul 10, 2018 6:36 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

. AJCC DEFINITIONS T3: The tumor has grown through the muscularis propria and into the subserosa, which is a thin layer of connective tissue beneath the outer layer of some parts of the large intestine, or it has grown into tissues surrounding the colon or rectum. T4a: The tumor has grown into the ...
by emkaye
Tue Jul 10, 2018 12:35 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

So I was able to glean more information from the oncologists office visit notes. Some of this was not discussed face to face in her visit: Surgical pathology: 12.5 cm, grade 2 Adenocarcinoma. Involving the pericolonic tissue. No evidence of perineural or lymphovascular invasion. No evidence of bowel...
by emkaye
Tue Jul 10, 2018 12:32 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

So I was able to glean more information from the oncologists office visit notes. Some of this was not discussed face to face in her visit: Surgical pathology: 12.5 cm, grade 2 Adenocarcinoma. Involving the pericolonic tissue. No evidence of perineural or lymphovascular invasion. No evidence of bowel...
by emkaye
Tue Jul 10, 2018 12:27 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

Interesting... this is the first I've heard of NextGen and it indeed sounds promising. Son has been working with it for about five years but they were in the game pretty early. Son said that RT-PCR can be used with any kind of sequencing. With NextGen sequencing, though, you could just look at all ...
by emkaye
Tue Jul 10, 2018 10:31 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

This is what I received from the Doctor that did the Genomic Tumor pathology for me: The first assay analyzes RNA to look for expressed transcripts containing sequences from two different genes. This is to look for fusion transcripts as a result of translocations. An example of a commonly recognize...
by emkaye
Tue Jul 10, 2018 9:05 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

If the Oncotype order is for NextGen sequencing, then it should do the complete sequence of the tumor genome. In previous generation sequencing, you ordered one or a few tests at a time and they did those tests individually. NextGen gets the whole genome and then you look for known cancer mutations...
by emkaye
Mon Jul 09, 2018 12:29 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

The biopsy is a block and it should be at the hospital where you had it done. They may use some of it up for the first pathology test. If there's enough leftover, it can be sent to another lab or hospital to do the Genomic Tumor Testing (Onctotype DX in your case). I had this done - my biopsy was t...
by emkaye
Sun Jul 08, 2018 3:38 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

Yes it is possible to send everything to a major cancer center. By everything I mean, all scans, e-rays, colonoscopy results, pathology results, blood work. When they remove the tumor, they place it in slides and what they call blocks. These can also be sent to a major cancer center. Hospitals usua...
by emkaye
Sun Jul 08, 2018 3:29 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

This looks like the tumor was a T3 and 3mm from the anterior abdominal wall adhesion. I don’t see where it says the tumor itself adhered to the wall. This would place the stage at 2A, which is questionable when it comes to chemo. The distance of 3mm from the margin and Grade 2 (moderate) might push...
by emkaye
Sun Jul 08, 2018 3:24 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

retiredteacher wrote:Was this rectal or colon?
Terri

Colon
by emkaye
Fri Jul 06, 2018 6:05 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

Thanks everyone for your advice. This is helping quite a bit! My issue is mom doesn't want a second opinion and doesn't want to travel. So that leaves us with a local hospital. HOWEVER, if we can have a 2nd pathology review done at a major cancer hospital with report sent to her local oncologist tha...
by emkaye
Fri Jul 06, 2018 3:46 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Re: Are we doing everything we can?

Yes I too think it would be prudent to send the path results to another hospital for a second look. We live close to a major university hospital with a cancer center. The surgery was done by a small local hospital. That's why I feel a bit uneasy about things. I too am confused when he said it grew t...
by emkaye
Fri Jul 06, 2018 1:10 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Are we doing everything we can?
Replies: 29
Views: 4383

Are we doing everything we can?

Mom had her appointment with the oncologist today. He went over the pathology report thoroughly and answered all our questions, however he is still not clear as whether to chemo or no. Her mass was very large (12.5 cm) and grew outside of the colon wall into the abdominal wall and small intestine. T...
by emkaye
Thu Jun 28, 2018 7:49 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: My mom is dying
Replies: 24
Views: 6494

Re: My mom is dying

So sorry to hear this. Will say a prayer for you and your mom.

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